Search
for

    Glossary T helper 1 cells

    specialized immune cells that produce cytokines to fight infections

    T helper 1 cells, often abbreviated as Th1 cells, are a subset of T cells that play a crucial role in the immune system by producing cytokines like interferon-gamma (IFN-γ). These cytokines help activate macrophages and are essential for defending against intracellular pathogens such as viruses and certain bacteria. Th1 cells are also involved in the pathogenesis of autoimmune diseases by promoting inflammation.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Frontal fibrosing alopecia shows robust T helper 1 and Janus kinase 3 skewing 2020 · 34 citations
    2. CD4 T cells from mice with alopecia areata express an effector like phenotype and can transfer disease The Journal of Immunology · 2023 · 1 citations
    3. Role of regulatory T cells in psoriasis pathogenesis and treatment British Journal of Dermatology · 2020 · 273 citations
    4. PD-1+CXCR5−CD4+T cells are correlated with the severity of systemic lupus erythematosus Rheumatology · 2019 · 71 citations
    5. Identification of Biomarkers in Affected Hair Follicles from Chronic Discoid LupusErythematosus by Weighted Gene Co-Expression Network Analysis Research Square (Research Square) · 2022
    6. Identification of Biomarkers in Affected Hair Follicles from Chronic Discoid Lupus Erythematosus by Weighted Gene Co-Expression Network Analysis Research Square (Research Square) · 2022
    7. Sebaceous Gland, Hair Shaft, and Epidermal Barrier Abnormalities in Keratosis Pilaris with and without Filaggrin Deficiency ˜The œAmerican journal of pathology · 2015 · 23 citations
    8. Results of stage I in a phase II randomized bilateral comparison of bexarotene 1% topical gel in alopecia areata Journal of the American Academy of Dermatology · 2005
    9. Decision letter: Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage 2021
    10. CLINICAL AND LABORATORY EVALUATION OF AIDS TRICHOPATHY International Journal of Dermatology · 1993 · 35 citations
    11. A humanized IL-2 fusion protein enhances T regulatory cells in vivo and restrains disease in a murine model of Alopecia Areata 4760 The Journal of Immunology · 2025
    12. Alopecia Areata: A Complex Cytokine Driven Disease 2020 · 3 citations
    13. Lupus comédonien Annales de Dermatologie et de Vénéréologie · 2007 · 7 citations
    14. The effect of 5-α reductase inhibitor on Th1, Th2, and Th17 cell-related inflammatory response in BPH World Journal of Urology · 2023 · 1 citations
    15. A case of bullous pemphigoid in a malignant melanoma patient following an increased Th2/Th1 ratio in peripheral blood cells after nivolumab treatment European Journal of Dermatology · 2023 · 1 citations
    16. Imbalance of T‐helper 17 and regulatory T cells in patients with alopecia areata The Journal of Dermatology · 2015 · 62 citations
    17. Plain language summaries British Journal of Dermatology · 2016
    18. MicroRNA-1246 Inhibits NFATc1 Phosphorylation and Regulates T Helper 17 Cell Activation in the Pathogenesis of Severe Alopecia Areata 2023
    19. The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1 New England Journal of Medicine · 2024 · 71 citations
    20. The Role of T‐Helper 17 Cells and Regulatory T Cells in Acute Diffuse and Total Alopecia: The Increased Function of Regulatory T Cells May Explain the Favorable Prognosis The Journal of Dermatology · 2025 · 1 citations
    21. T <sub>H</sub> 1 effector CD4 T cells rely on IFN-γ production to induce alopecia areata Science Advances · 2025
    22. Regulatory T cell dysfunction and immunotherapeutic breakthroughs in type 1 diabetes Frontiers in Endocrinology · 2026 · 2 citations
    23. Antigen-Specific Regulatory T Cells and Low Dose of IL-2 in Treatment of Type 1 Diabetes Frontiers in immunology · 2016 · 23 citations
    24. The potential of regulatory T cell-based therapies for alopecia areata Frontiers in Immunology · 2023
    25. T Cells Promote Distinct Transcriptional Programs of Cutaneous Inflammatory Disease in Keratinocytes and Dermal Fibroblasts Journal of Investigative Dermatology · 2025 · 2 citations
    26. The imbalance between Type 17 T-cells and regulatory immune cell subsets in psoriasis vulgaris Frontiers in Immunology · 2022 · 49 citations
    27. Induction of T cell exhaustion by JAK1/3 inhibition in the treatment of alopecia areata Frontiers in immunology · 2022 · 13 citations
    28. 290 Brepocitinib improves cicatricial alopecia and downregulates key T-helper biomarkers Journal of Investigative Dermatology · 2024
    29. Mesenchymal Stem Cells from Mouse Hair Follicles Inhibit the Development of Type 1 Diabetes International Journal of Molecular Sciences · 2024
    30. Class IIa HDAC4 and HDAC7 cooperatively regulate gene transcription in Th17 cell differentiation Proceedings of the National Academy of Sciences · 2024 · 16 citations