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Lambs' skin showed similar but more severe responses to a second orf virus infection, involving immune cells and new skin formation.

The mtDNA N haplogroup is linked to a higher risk of late-onset lupus and specific symptoms in Han Chinese women.

Distinguishing drug-induced lupus from systemic lupus is challenging and requires careful monitoring.

About 8% of people with systemic lupus erythematosus have chronic scarring alopecia, with certain symptoms and positive antibodies increasing the risk, while immunosuppressants may lower it.

Tjalma Syndrome is a rare condition in people with lupus, causing fluid buildup and high CA-125 levels, but not due to tumors.

A woman in Sri Lanka was diagnosed with lupus after presenting with protein loss from the gut and other symptoms.

A scalp biopsy revealed systemic amyloidosis in a woman who initially seemed to have a common hair loss condition.

Skin issues like hair loss, rash, and sensitivity to sunlight are key signs of lupus activity.

Women with lupus experienced non-scarring hair loss with fewer hair follicles, and the test for lupus in hair was not helpful.

Finasteride treatment lowers urine androgen and prostaglandin levels, making them potential markers for effectiveness.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Chemotherapy can cause permanent, non-reversible hair loss similar to pattern baldness.

Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.

No systemic treatment for alopecia areata has strong evidence of effectiveness.

Most pregnant women experience skin darkening and hair changes, with these effects usually going away after giving birth.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Early detection and stopping the drug are key to managing DRESS, and careful monitoring is important due to possible severe reactions.

Older adults commonly experience wrinkles, itchy skin, psoriasis, fungal infections, skin growths, grey hair, hair loss, and nail ridging, but no skin cancer was found in this group.

Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.

Hair loss in lupus is different from hair loss in alopecia areata and may indicate lupus activity.

Topical clobetasol is recommended over mycophenolate mofetil for treating Lichen Planopilaris due to better safety and patient satisfaction.

Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.

The article concludes that correctly diagnosing systemic causes of hair loss requires a detailed clinical evaluation and a systematic diagnostic approach.

Adding a small amount of TPGS to minoxidil can help hair growth, but too much TPGS reduces this effect and increases minoxidil in the blood.