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A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Growth factors are crucial for hair development and could help treat hair diseases.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

LCN may improve finasteride delivery for hair loss treatment.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Certain drugs that block specific enzymes can help treat prostate diseases.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

New compounds may soon be tested to treat excessive hair growth in women.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Low-dose finasteride reduces excessive hair growth in teenage girls safely and affordably.

Anabolic steroid users may face higher risk of severe COVID-19.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

The article concludes that dermatologists should prescribe lifestyle drugs carefully and consider mental health treatments for patients with disorders like BDD.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.