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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Growing human skin cells in a 3D environment can stimulate new hair growth.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Nerves are crucial for the regeneration of various body parts in many animals.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Noggin is necessary to start the hair growth phase in skin after birth.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

New effective scar treatments are urgently needed due to the current options' limited success.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

Minoxidil boosts hair growth by increasing cell production and survival.

Cathepsin L is essential for normal hair growth and development.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Nerves and chemicals in the body can affect hair growth and loss.