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The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Polycystic ovary syndrome affects about 6-10% of women, with varying symptoms and the need for standardized global definitions.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Fungi-produced compounds can change plant root growth.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

The 2003 guidelines suggest that while some treatments can regrow hair in alopecia areata, none alter the disease's progression, and wigs may be the best option for extensive hair loss.

Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

The study found that Frontal Fibrosing Alopecia affects a broader age range of women and early treatment can help stop hair loss.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.