research Tissue Engineering Strategies for Human Hair Follicle Regeneration: How Far From a Hairy Goal?
Fully regenerating human hair follicles not yet achieved.
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research High-Content Drug Screening for Rare Diseases
High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
research Women's Midlife Health: Reframing Menopause
The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.
research Applications and Risks of Nanomaterials Used in Regenerative Medicine, Delivery Systems, Theranostics, and Therapy
Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.
research The Eyelash Follicle Features and Anomalies: A Review
Eyelashes protect the eyes, but more research is needed to understand how.
research Promotion of Anagen, Increased Hair Density, and Reduction of Hair Fall in a Clinical Setting Following Identification of FGF5-Inhibiting Compounds via a Novel 2-Stage Process
New compounds were found to help increase hair growth and decrease hair loss.
research Injectable Self-Healing Ceria-Based Nanocomposite Hydrogel with ROS-Scavenging Activity for Skin Wound Repair
The hydrogel speeds up skin wound healing and helps regenerate tissue.
research Exploring Pericyte and Cardiac Stem Cell Secretome Unveils New Tactics for Drug Discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research Hair Removal Using a Long-Pulsed Alexandrite Laser
The long-pulsed alexandrite laser is effective for hair reduction, particularly for light-skinned individuals with dark hair, but caution is needed for darker skin.
research Apoptotic Cells Represent a Dynamic Stem Cell Niche Governing Proliferation and Tissue Regeneration
Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.
research Stem Cells and Aberrant Signaling of Molecular Systems in Skin Aging
Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
research Steroid Sulfatase Inhibitors: Therapeutic Applications and Development
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
research Interventions for Morphea
Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.
research Retinoid-Mediated Stimulation of Steroid Sulfatase Activity in Myeloid Leukemic Cell Lines Requires RARα and RXR and Involves the Phosphoinositide 3-Kinase and ERK-MAP Kinase Pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
research Application of Nanoemulsions in Cosmetics
Nanoemulsions improve stability and delivery of active ingredients in cosmetics for skin and hair care.
research Regenerative Medicine and Hair Loss: How Hair Follicle Culture Has Advanced Our Understanding of Treatment Options for Androgenetic Alopecia
Hair follicle culture helps develop new treatments for hair loss.
research Unraveling the Molecular Mechanisms of Hair and Nail Genodermatoses
Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.
research Normal and Aging Hair Biology and Structure: Aging and Hair
Hair gets thinner, grayer, and changes texture with age due to genetics, environment, and cellular changes, affecting the growth cycle.
research Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
research Apocrine Sweat Gland Obstruction by Antiperspirants Allowing Transdermal Absorption of Cutaneous Generated Hormones and Pheromones as a Link to the Observed Incidence Rates of Breast and Prostate Cancer in the 20th Century
The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.
research Structural Characterization of Polymorphs and Molecular Complexes of Finasteride
Finasteride's molecular and crystal structures help develop new drug formulations.
research Engineering Cell-Derived Matrices: From 3D Models to Advanced Personalized Therapies
3D cell-derived matrices improve tissue regeneration and disease modeling.
research Investigation of Intermolecular Interactions in Finasteride Drug Crystals in View of X-ray and Hirshfeld Surface Analysis
Finasteride crystals are held together by hydrogen bonds and weak interactions, forming synthon pseudopolymorphs.
research Specific Inhibition of FGF5-Induced Cell Proliferation by RNA Aptamers
RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.
research Does Finasteride Have a Preventive Effect on Chronic Bacterial Prostatitis? Pilot Study Using an Animal Model
Finasteride may help prevent chronic bacterial prostatitis, with better results when combined with antibiotics.
research Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model
Mouse stem cells from hair follicles can improve wound healing and reduce scarring.
research Wnt Signaling Activation: Targets and Therapeutic Opportunities for Stem Cell Therapy and Regenerative Medicine
Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
research The Impact of 5α-Reductase Inhibitor Use for Male Pattern Hair Loss on Men's Health
Hair loss drugs may cause sexual issues and infertility in men.
research Nutraceutical and Functional Scenario of Wheat Straw
Wheat straw is valuable for its health benefits and various industrial uses.
research Mesothelial Stem Cells and Stromal Vascular Fraction for Skin Rejuvenation
Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.