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The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

PCOS is common among Chinese women of reproductive age and linked to serious metabolic and reproductive issues, especially in obese women.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Estrogen therapy can reduce skin aging but has cancer risks.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Many women in southern China have polycystic ovary syndrome, with some symptoms differing from Western women.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

An mFG score of 5 or more indicates above-normal hair growth in Southern Chinese women.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.