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Higher doses of oestradiol implants improve bone density in postmenopausal women.

Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.

Finasteride caused bleeding in a man, which stopped after stopping the drug.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Targeting colon cancer stem cells might lead to better treatment results.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Diet changes can protect against harmful environmental effects on fetal development.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Minoxidil effectively lowers blood pressure with few side effects.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

FFA is more common in postmenopausal women, can affect younger women, and may stabilize over time.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.