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High doses of certain vitamins can cause serious side effects and health risks.

DA-9401 protects against hair loss, improves organ function, and prevents infertility caused by finasteride.

Gene differences affect finasteride side effects in men with hair loss.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

Finasteride effectively treats baldness but may cause sexual side effects.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Finasteride effectively treats hidradenitis suppurativa for most patients.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.