215 citations,
November 2006 in “Journal of The American Academy of Dermatology” Dutasteride more effective for hair growth, but has more side effects than finasteride.
162 citations,
April 2016 in “The Lancet Diabetes & Endocrinology” Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.
149 citations,
June 2002 in “Veterinary record/The veterinary record” Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.
125 citations,
January 1999 in “Drugs” Finasteride effectively treats baldness but may cause sexual side effects.
118 citations,
May 2003 in “Toxicological Sciences” Exposure to finasteride in the womb caused lasting reproductive issues in male rats.
116 citations,
December 2013 in “The Journal of Pediatrics” Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.
99 citations,
April 2005 in “Journal of Dermatological Treatment” Finasteride effectively treats hidradenitis suppurativa for most patients.
86 citations,
March 1993 in “Toxicology and Applied Pharmacology” Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
75 citations,
November 2009 in “Gynecological Endocrinology” Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.
62 citations,
March 2013 in “JAMA Dermatology” Finasteride reduces Hidradenitis Suppurativa flare-ups in children and teens, but long-term safety is unknown.
54 citations,
August 2009 in “Dermatologic Surgery” Modern hair transplants use small grafts for a natural look and drugs to prevent further loss, with high patient satisfaction.
52 citations,
September 1996 in “Obstetrics & Gynecology” People often struggle to consistently use contraceptives and other medications, and long-acting options might be better for those who want to avoid daily doses.
39 citations,
January 2012 in “Indian Dermatology Online Journal” Finasteride may cause sexual side effects like erectile dysfunction, but they are reversible and affect less than 2% of men.
31 citations,
November 2000 in “Journal of the European Academy of Dermatology and Venereology” Skin problems can be linked to sexual abuse, requiring careful medical and psychological evaluation.
29 citations,
September 2014 in “Current Opinion in Endocrinology, Diabetes and Obesity” Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.
28 citations,
November 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The normal human prostate does not significantly affect blood DHT levels.
28 citations,
January 1991 in “Reproductive Toxicology” Finasteride temporarily lowers male rat fertility without affecting libido.
26 citations,
July 2019 in “Fertility and Sterility” Reproductive gynecologists are the main referrers for male infertility evaluations in North America.
19 citations,
July 2006 in “Physiology & Behavior” Finasteride slows down motherly behavior in first-time pregnant rats.
17 citations,
January 1986 in “Acta obstetricia et gynecologica Scandinavica” Spironolactone can reduce hair growth and testosterone in hirsutism, but is less effective than combined treatments.
16 citations,
January 2019 in “Kansas journal of medicine” Healthcare providers need better education and policies to serve transgender individuals effectively.
15 citations,
November 2015 in “Pharmacopsychiatry” α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.
14 citations,
December 2007 in “Journal of The European Academy of Dermatology and Venereology” The article concludes that dermatologists should prescribe lifestyle drugs carefully and consider mental health treatments for patients with disorders like BDD.
9 citations,
January 2018 in “American Journal of Men's Health” Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.
7 citations,
January 2019 in “Headache” Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.
3 citations,
June 2018 in “International Journal of Clinical Pharmacy” Baby born healthy despite mom taking finasteride, but more research needed.
2 citations,
August 2016 in “Experimental Dermatology” Finasteride treats baldness but may cause lasting sexual side effects.
2 citations,
June 2012 in “Digestive Diseases and Sciences” Finasteride and methadone don't increase advanced liver disease risk in HCV+ male veterans.
2 citations,
September 2008 in “Fertility and Sterility” Women with PCOS and higher BMI, especially those with morbid obesity, are at greater risk for depression.
1 citations,
January 2022 in “Saudi journal of medicine” PCOS is a major cause of infertility in women of childbearing age.