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Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

The definition of Polycystic Ovary Syndrome may change with new research, and careful screening is key for managing the condition.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Blocking β-catenin in skin cells improves hair growth during wound healing.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Women with PCOS are more likely to suffer from depression, anxiety, and stress.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.