5 citations
,
December 2015 in “Dermatologic Therapy” In this study, topical phenylephrine significantly reduced hair shedding and increased the force needed to pluck hair in women undergoing cosmetic procedures, suggesting its potential utility for traction alopecia.
6 citations
,
December 2016 in “Journal of Obsessive-Compulsive and Related Disorders” This study found that adults with trichotillomania did not show differences in pain tolerance or exhibit analgesia to cold pressor pain compared to healthy controls.
7 citations
,
August 2017 in “Journal of dermatological science” This study found that sorafenib increased mast cell number and degranulation in skin, suggesting PI3K signaling and SCF production may underlie its adverse cutaneous reactions.
September 2024 in “Journal of the American Academy of Dermatology” This study reports that oxytocin receptor expression in keratinocytes shows a potential relationship with touch sensory neurons, suggesting a role in skin sensitivity and the broader function of sensory neurons.
April 2017 in “InTech eBooks” This review discusses potential mechanisms and treatments for trichodynia, noting a lack of strong literature support and reporting no new clinical results; the authors highlight several hypotheses and available treatment options.
The man's scalp tightness after hair surgery affects his life and work, and it's unclear if it's due to the surgery or a mental health issue.
January 2023 in “Indian dermatology online journal” This case study highlights that sarcoidosis lesions can occur following hair removal by waxing, emphasizing the need to consider superficial traumas as potential triggers for cutaneous sarcoidosis.
September 2026 in “International Journal of Dermatology” This review discusses the clinical presentation, diagnosis, and treatment of scalp dysesthesia, highlighting a potential neuropathic component and the inconsistent efficacy of various management strategies without reporting new clinical results.
1 citations
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February 2021 This study observed that using ice pack compression or a vibration anesthesia device reduced pain during inactivated PRP scalp injections in patients with alopecia, suggesting both as inexpensive and accessible pain-relief options.
In an animal study, researchers observed that a Chromolaena odorata layered-nitrile rubber transdermal patch significantly improved wound contraction, protein, hexosamine, and uronic acid levels, and collagen deposition in healing excision wounds in rats compared to a control group with an empty patch.
July 2011 in “Journal of Pediatric and Adolescent Gynecology” This report discusses a teenager with blistering of localized epidermolysis bullosa simplex—Weber Cockayne type, recommending referral to dermatology, and includes no new clinical trials or broader conclusions.
1 citations
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April 2024 in “Lasers in Surgery and Medicine” This study developed a 3D computational model to simulate how skin, fat, and muscle deform under suction, reporting that as suction pressure increased, skin thickness decreased, while fat thickness increased, and muscle thickness remained stable, closely aligning with experimental results.
January 2005 in “中华医学杂志:英文版” This study found that residual sweat glands in hypertrophic scar tissues may regenerate from adult epidermal stem cells or residual glands after burn injury.
January 1995 in “Seoul National University Open Repository (Seoul National University)” This study found that skin sulfhydryl oxidase plays a role in keratinization and may contribute to skin's protective functions, with its expression influenced by irritants and differentiation modifiers.
14 citations
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March 2014 in “Journal of the Society of Cosmetic Scientists of Korea” This study suggests that ethanol extracts from ten selected Korean herb medicines reduced inflammatory markers in a cell model and did not cause skin irritation in human testing, indicating potential cosmetic use for irritation prevention.
In this study, researchers found that an injectable solution of low-molecular-weight hyaluronic acid and amino acids significantly improved skin rejuvenation and elasticity in the labia majora of post-menopausal women over 12 weeks, with a reported 25% or greater aesthetic improvement and high patient satisfaction.
1 citations
,
September 2022 in “European Journal of Dermatology” This study identified a novel splice-site variant of the LAMB3 gene that may cause junctional epidermolysis bullosa, suggesting gene sequencing is essential for accurate diagnosis.
January 2009 in “Journal of musculoskeletal pain” This case report describes a patient who developed herpes zoster on the right knee following an intraarticular sodium hyaluronate injection, suggesting a possible link between the injection and the infection.
May 2011 in “Value in Health” This study found that the oral Janus kinase inhibitor CP-690,550 has a direct effect on reducing pruritus in patients with psoriasis, independent of clinician-assessed improvements in psoriasis severity.
140 citations
,
February 2014 in “Neuron” This study found that the opioid system, particularly via the delta opioid receptor, broadly regulates cutaneous mechanosensation, including touch, and suggests targeting this receptor could alleviate injury-induced mechanical hypersensitivity.
5 citations
,
July 1999 in “Journal of Anatomy” This study observed that methylene blue staining and zinc iodide-osmium tetroxide techniques effectively revealed anatomical details of intraepidermal nerve fibre endings in the rat's mystacial pad, suggesting their potential role in mechanoreception.
2 citations
,
August 2024 in “Preprints.org” This case study reports a potential link between ichthyosis and scalp paresthesia, noting that fluocinolone, a synthetic corticosteroid, was effective in reducing paresthesia episodes, suggesting its possible role in the symptomatic treatment of this condition.
16 citations
,
December 2006 in “Chinese Medical Journal” This case report describes a 12-year-old boy with congenital insensitivity to pain with anhidrosis and progressing acro-osteolysis, highlighting the severe complications and the necessity for early intervention.
This article provides no abstract or new findings and focuses on a patient registry related to spasticity care.
November 2021 in “Journal of the European Academy of Dermatology and Venereology” This study found that children with COVID-19 experienced more frequent acral ischemic lesions, whereas telogen effluvium was the most common skin manifestation in adults.
20 citations
,
February 1991 in “Archives of dermatology” In this study, researchers found that high-dose tryptophan ingestion before symptom onset may be linked to clinical features resembling eosinophilia-myalgia syndrome in patients with eosinophilic fasciitis.
135 citations
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May 2002 in “Anesthesiology” This review examines current knowledge and treatment strategies for complex regional pain syndrome type I in adults, emphasizing clinical aspects and highlighting the lack of consensus on therapeutic approaches, without presenting new clinical findings.
1 citations
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March 2024 in “Skin health and disease” This study found that vibration assisted analgesia reduced pain during intralesional corticosteroid therapy for hair loss, enabling treatment in a broader range of patients, including those with needle phobia.
21 citations
,
July 2011 in “Journal of the American Academy of Dermatology” This study reported a drug-induced pityriasis rubra pilaris-like eruption in a patient treated with sorafenib, suggesting a possible effect of sorafenib on keratinocyte biology.
July 2024 in “Medical alphabet” The authors concluded that "burning scalp" syndrome lacks general treatment recommendations, but therapeutic cosmetics showing antipruritic and anti-inflammatory effects may offer promise for long-term management and prevention.