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Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.

New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.

RNA can be extracted from horsehair roots for analysis.

Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Myoblast transplantation shows promise for treating various muscle and heart conditions.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

SLVs help maintain muscle stretch sensitivity and could aid in treating hypertension and muscle spasticity.

Glucocorticoids for progressive muscular dystrophy in children don't improve muscle strength or function but do increase certain side effects.

A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

Many men misuse oral contraceptive pills for things like hair growth and muscle gain.

A new mutation in the PLEC gene causes a rare condition with skin blistering, muscle weakness, and hair loss.

Testosterone is important for male sexual traits, reproduction, muscle and bone health, blood production, and metabolism, and works both directly and after being changed into other hormones.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.

Alopecia is a key indicator of thallium poisoning.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Men need higher doses and tailored injection techniques for botulinum toxin treatments due to their unique facial features.

Low-level laser therapy using near-infrared light may help heart conditions and promote healing by releasing nitric oxide.

Some supplements and hormones can increase hair loss by raising DHT levels.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.