107 citations
,
September 2002 in “Journal of Investigative Dermatology” This study identified a distinct "exogen" phase in the hair cycle during which hair shedding occurs, primarily coupled with the anagen phase, rather than as part of the telogen phase.
34 citations
,
March 2001 in “Cleveland Clinic Journal of Medicine” This article reviews the triggers, diagnosis, and management of telogen effluvium in men and women, emphasizing the role of patient education and reassurance, but presents no new clinical findings.
8 citations
,
April 2024 in “Cureus” This review compares the CO2 and Er:YAG laser treatments for acne scars, noting that while CO2 lasers offer deeper tissue penetration for severe scars, Er:YAG lasers pose a lower risk of post-inflammatory hyperpigmentation, and recommends personalizing treatments and considering combination therapies.
8 citations
,
July 2020 in “BMC genomics” In this study, ceruloplasmin and keratin 4 were identified as markers that differentiate between growing and resting phases in cashmere goat hair follicles, with keratin 4 being a potential marker for the onset of a new hair cycle.
7 citations
,
December 2020 in “Clinics in Dermatology” This article reviews the use of various treatments for alopecia and their potential impact on COVID-19 outcomes, emphasizing the importance of patient registries in generating real-world evidence; it reports no new results.
6 citations
,
May 2020 in “Nutrients” This review discusses the effects of calorie restriction on skin aging, highlighting its potential to benefit skin health by reducing age-related and photo-induced changes, although the impact of certain diets remains unexplored.
6 citations
,
September 2018 in “Journal of Dermatological Treatment” This review examines the FDA's 510(k) approval process for low-level laser therapy devices used in treating androgenetic alopecia and reports no new clinical findings.
1 citations
,
March 1989 in “Proceedings of the British Society of Animal Production” This article reviews how photoperiod, melatonin, and prolactin influence moult timing in mammals, focusing on cashmere goats, but reports no new experimental findings.
May 2023 in “Journal of The American Academy of Dermatology” This correspondence outlines a research aim to evaluate the usefulness of laboratory testing for telogen effluvium to assist in forming evidence-based treatment guidelines, though results are not provided in the abstract.
1 citations
,
December 2020 in “International journal of molecular sciences” This study suggests that biallelic loss of the Hedgehog signaling repressor Patched alone in Keratin 5+ epidermal cells is insufficient to drive basal cell carcinoma development unless exogenous stimuli trigger accumulation of BCC precursor cells.
January 2026 in “Open Science Framework” This study examines various methodological factors affecting hair cortisol concentration analysis, finding inconsistent results on the impact of factors like resuspension solution, hair weight, extraction duration, and hair-cutting method.
418 citations
,
September 2012 in “Nature” This study reports the first instance of skin autotomy in mammals, specifically in African spiny mice, and suggests they may possess a greater regenerative capacity than previously understood, possibly offering insights for regenerative medicine.
234 citations
,
December 1996 in “Journal of The American Academy of Dermatology” The authors concluded that chronic telogen effluvium in middle-aged women presents distinct clinical and histological features that differ from androgenetic alopecia and acute telogen effluvium.
56 citations
,
January 2001 in “Dermatology” This study introduces the concept of teloptosis, which influences hair shedding during the telogen phase and affects hair density, highlighting that early or delayed teloptosis has noticeable effects.
51 citations
,
January 2004 in “Skin Pharmacology and Physiology” This review discusses various techniques for evaluating hair shedding and alopecia but reports no new clinical results. The authors emphasize the value of specific clinical and instrumental methods in assessing hair growth.
45 citations
,
April 2009 in “Journal of anatomy” This study examined the complex morphology of the cornified claw sheath in domesticated cats, uncovering structures and growth patterns that help maintain sharp claw tips essential for climbing and prey capture.
43 citations
,
October 2002 in “International Journal of Cosmetic Science” This study found that 1% ketoconazole and 1% piroctone olamine shampoos increased hair shaft thickness and reduced hair shedding in men with telogen effluvium and androgenic alopecia associated with dandruff.
41 citations
,
February 2021 in “Cureus” This study found that in males with mild COVID-19, treatment with dutasteride, along with standard therapy, may reduce viral shedding and inflammation compared to placebo.
37 citations
,
January 2009 in “Dermatology” This study reports that hair growth and shedding in healthy women show annual seasonal patterns, with the highest shedding in summer and a less pronounced peak in spring.
32 citations
,
April 2015 in “British Journal of Dermatology” This article discusses hair shedding in women and does not offer new research results; it highlights the need for objective criteria to define excessive hair shedding.
22 citations
,
January 2015 in “Dermatology Research and Practice” This study found that an oral marine protein supplement significantly increased hair growth and reduced hair shedding in women with temporary thinning hair over 90 days compared to a placebo.
19 citations
,
May 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that mice lacking the type 3 IP(3) receptor in their hair follicles experienced repetitive hair loss and regrowth, indicating disrupted hair-cycle regulation potentially linked to specific signaling pathways.
16 citations
,
February 2017 in “Dermatology and Therapy” This study established and validated a visual scale to assess hair shedding in women with thick hair, finding it effective in distinguishing greater hair loss among women with female pattern hair loss compared to those without.
14 citations
,
January 1999 in “Dermatology” This study found that the wash test reliably measures hair shedding in children, with the number of shed hairs increasing with age and suggesting a potential early onset of androgenetic alopecia.
9 citations
,
January 2006 in “American Journal of Clinical Dermatology” This study found that Malassezia carriage was significantly more common among participants experiencing hair shedding, suggesting a potential link between this fungal presence and hair loss.
7 citations
,
October 2016 in “Dermatologic Therapy” This study quantified hair shedding in women without female pattern hair loss and found that about 40% experienced excessive shedding during hair washing, emphasizing the need for further research into this common concern.
6 citations
,
August 2021 in “International Journal of Cosmetic Science” This study concluded that a regimen containing functional antioxidants and barrier-enhancing agents reduced hair shedding and increased perceived hair fullness in participants with self-perceived hair thinning over 24 weeks.
3 citations
,
March 2022 in “Annals of Medicine” This study suggests that telogen effluvium is more closely related to the severity of COVID-19 and associated inflammation than to hormonal factors, with women showing a higher prevalence.
3 citations
,
July 2019 in “Journal of Cosmetic Dermatology” This study found that a shampoo with a selective TAAR agonist reduced hair shedding during brushing by 31% in women and contracted the arrector pili muscle.
2 citations
,
January 2022 in “Clinical, Cosmetic and Investigational Dermatology” This study found that a refined wash test can effectively differentiate shedding hair characteristics among normal individuals, and patients with androgenetic alopecia or telogen effluvium, aiding in diagnosis and monitoring.