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The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Excess male hormones in postmenopausal women can cause health issues and increase the risk of heart disease and diabetes; treatment depends on the cause.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.

The Free Androgen Index (FAI) is the best indicator of early hair loss in men before age 30.

Lower SHBG levels may increase the risk of PCOS.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.

Vitamin D deficiency is linked to a higher chance of metabolic syndrome in women with PCOS.

Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.

SHBG binding properties are unchanged in male liver cirrhosis patients.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Eyelashes are important for looks and eye protection, and more people are treating sparse eyelashes; more research is needed to understand eyelash biology and improve treatments.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

The document concludes that skin and hair changes in small animals are often due to hormonal imbalances and recommends regular baths and antibiotics for associated infections.

Losing weight, possibly through bariatric surgery, is key to improving PCOS and hyperandrogenism symptoms in obese patients.

Women with hair thinning have disrupted steroid hormone levels, but this doesn't often show as other health issues. More research is needed on hormone balance in this condition.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.

Different types of hair loss in dogs and cats have various causes and treatments, with outcomes ranging from good to uncertain.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

People with hair loss have higher risk of high blood sugar and diabetes, and lower levels of a specific hormone.

Testosterone increases muscle mass regardless of DHT conversion blocking.