193 citations
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February 2015 in “Nature Communications” Fungi-produced compounds can change plant root growth.
75 citations
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June 2019 in “International Journal of Molecular Sciences” This review discusses the therapeutic potential of costunolide for various diseases, highlighting its bioactivity and mechanisms, but it reports no new experimental results.
44 citations
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March 2012 in “Fitoterapia” In this study, germacrone from Curcuma aeruginosa showed anti-androgenic effects by inhibiting 5α-reductase, suggesting its potential as a lead compound for treating androgen-dependent disorders.
21 citations
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October 2017 in “Cell death and disease” This study found that the absence of the stress-responsive protein Sesn2 increased hair cell susceptibility to gentamicin in the inner ear, indicating Sesn2's potential protective role against aminoglycoside-induced damage.
15 citations
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November 2017 in “Drug Delivery and Translational Research” This study found that co-applying Curcuma aeruginosa extract or essential oil with minoxidil significantly increased minoxidil's skin penetration in an ex vivo setting, suggesting an improved topical treatment strategy for androgenic alopecia with greater efficacy and the potential for lower minoxidil doses.
5 citations
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January 2018 in “Skin Pharmacology and Physiology” This study found that a high sesquiterpene C. aeruginosa extract significantly reduced axillary hair growth in women compared to placebo with no apparent adverse effects.
2 citations
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January 2012 This study found that SESA oil significantly improved hair and scalp ailments more than coconut oil, with no adverse reactions reported during the study period.
January 2026 in “Scientific Reports” In this study, researchers found that sesamin, a component of sesamum, modulated the AR-MAPK-Wnt signaling pathway in DHT-stimulated HaCaT keratinocytes, demonstrating potential multi-target activity against molecular events in androgenetic alopecia.
July 2026 in “Clinical Cosmetic and Investigational Dermatology” In this study, a liposomal-encapsulated Sesbania grandiflora formulation significantly improved hair and scalp health in adults with hair loss over 180 days, showing enhanced hair density, thickness, growth rate, and tensile strength compared to placebo, with no related adverse events reported.
July 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that the liposomal Sesbania grandiflora formulation significantly improved hair and scalp health in adults with hair loss compared to placebo over 180 days, enhancing factors such as hair density, thickness, growth rate, and tensile strength, with no related adverse events reported.
January 2026 in “International journal of research and scientific innovation” This study reviewed a traditional siddha hair treatment using quail bone ash and sesame oil, observing reduced hair fall and stimulation of new growth, though it suggests further scientific and clinical validation is needed for these findings.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this review, researchers highlighted the potential of herbal hair oils made from rosemary (Rosmarinus officinalis) and black sesame (Sesamum indicum) as safe and effective alternatives to synthetic products, citing their antioxidant, anti-inflammatory, and nourishing properties that support scalp health and hair quality.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights the potential of herbal hair oil prepared with rosemary and black sesame for scalp health, hair strength, and appearance, emphasizing their antioxidant and nourishing benefits as a natural alternative to chemical formulations.
In this clinical trial, the researchers observed that a biotin and silica supplement reduced hair fall, increased hair growth rate, and improved skin elasticity, hydration, and nail quality over 90 days without adverse effects.
April 2025 in “International Journal of Pharmaceutical Sciences Review and Research” This study found that SesZen-Bio TM, a proprietary extract from Sesbania grandiflora leaves, increased proliferation of hair cells and hair shaft length in vitro and ex vivo, potentially due to activation of the Wnt/β-catenin signaling and stem cell differentiation pathways.
November 2024 in “International Journal of Research in Dermatology” SesZen-BioTM improves skin health and reduces signs of aging.
May 2024 in “Academia Open” In this study, conducted on male Wistar rats, high doses of white turi flower extract significantly increased sodium and potassium kidney levels, causing symptoms like lethargy and hair loss without fatalities, suggesting potential acute toxicity that warrants further research for long-term safety assessment.
April 2024 in “International journal of clinical trials” In this study, researchers found that a standardized extract of Sesbania grandiflora (SesZen-Bio™) improved hair density and thickness, as well as increased serum ferritin levels, over an 8-week period among participants, suggesting enhanced keratin production and follicle growth.
November 2023 in “L'Endocrinologo” This review examines the impact of polycystic ovary syndrome (PCOS) on women's sexual health, highlighting inconsistencies in existing research; it reports no new results.
May 2022 in “International Journal of Biochemistry Research and Review” The researchers characterized a plant-based biotin supplement, SesZenBioTM, from Sesbania agati leaves, predicting it may enhance hair follicle growth more effectively than synthetic biotin based on molecular interactions and its biotin content.
January 2019 in “Journal of Dermatology and Venereology” This study reports that topical pumpkin seed oil and sesame oil were both effective in treating alopecia areata, with no significant difference in effectiveness between the two after three months.
January 2018 in “Figshare” This study found that a high-sesquiterpene extract from Curcuma aeruginosa slowed axillary hair growth in women by 22% compared to placebo over 12 weeks, with results delayed by 6 weeks, and participants reported satisfaction without adverse effects.
December 2012 in “International Journal of Phytomedicine” This study found that SESA oil and capsules were associated with decreased hair fall and increased hair regeneration in patients with alopecia, without any reported adverse reactions over three months.
July 2026 in “Aesthetic Surgery Journal Open Forum” This study concluded that non-shaven follicular unit extraction with a pre-trimming method and large session transplantation is a safe and effective treatment for advanced androgenetic alopecia.
This study reported that black sesame oil significantly stimulated hair regrowth in mice, suggesting its potential for promoting hair growth or preventing hair loss in humans.
December 2004 in “Neuropsychopharmacology” This study found that chronic ethanol exposure and withdrawal alter the expression and function of GABA-A receptors in rat hippocampal and cerebellar neurons, suggesting different roles for these receptors in controlling tonic inhibition.
January 1998 in “Lasers in Surgery and Medicine” This study found that both 5-ALA and Photofrin can effectively destroy human microvascular endothelial cells in vitro and cause tissue necrosis in vivo, with Photofrin showing greater efficacy at lower concentrations or power densities.
6 citations
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January 2016 in “Journal of lasers in medical sciences” This study found that a single session of low level laser irradiation did not significantly affect hair growth outcomes in transplanted follicles for patients with androgenic alopecia.
1 citations
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September 2003 in “The Journal of the American Animal Hospital Association/Journal of the American Animal Hospital Association” This abstract describes a study that found fluoxetine HCl can be absorbed through cat skin when applied as a transdermal gel, though its bioavailability was about 10% compared to oral dosing.
February 2025 in “JAAD International” Five monthly sessions of minoxidil-dutasteride-copper peptide tattooing significantly improve hair regrowth in men with androgenetic alopecia.