research Exogenous Calreticulin Improves Diabetic Wound Healing
Applying calreticulin can speed up wound healing in diabetics.
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research Allopregnanolone Promotes Proliferation and Differential Gene Expression in Human Glioblastoma Cells
Allopregnanolone increases growth and changes gene activity in human brain cancer cells.
research Comparison of Metformin and N-Acetylcysteine on Metabolic Parameters in Women with Polycystic Ovarian Syndrome
N-acetylcysteine was more effective and had fewer side effects than metformin for improving insulin resistance in women with PCOS.
research Alopecia Triangularis Congenita in Combination with Androgenetic Alopecia
Hair loss improved with treatment and successful transplant.
research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men
Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.
research Infertility in Polycystic Ovary Syndrome: Focus on Low-Dose Gonadotropin Treatment
Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.
research Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model
Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.
research ROBO4 Deletion Ameliorates PAF-Mediated Skin Inflammation by Regulating the mRNA Translation Efficiency of LPCAT1/LPCAT2 and the Expression of PAF Receptor
Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.
research Main Plenary Sessions: Summaries of Papers
UK medical students lack dermatology education, liver biopsy patients with risk factors show more fibrosis, and certain fungi resist drugs due to melanin; genetics may influence female hair loss.
research Interrelation of Immunity and Tissue Repair or Regeneration
The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
research Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research
New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide
Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
research Anti-Zika Activity of a Library of Synthetic Carbohydrate Receptors
Some synthetic carbohydrate receptors, especially compounds 3 and 15, show strong potential for treating Zika virus.
research Polymeric Micelle Mediated Follicular Delivery of Spironolactone: Targeting the Mineralocorticoid Receptor to Prevent Glucocorticoid-Induced Activation and Delayed Cutaneous Wound Healing
Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
research Comprehensive Overview of Rheumatology Studies: Ottawa, Ontario, Canada, February 13–16, 2013
The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.
research FLCN Regulates Transferrin Receptor 1 Transport and Iron Homeostasis
FLCN helps control iron levels in cells.
research Abstracts of 42nd National Conference of Association of Clinical Biochemists of India (ACBICON 2015)
The conference presented findings on how vitamin D levels, genetic factors, and lifestyle choices like smoking and yoga affect various health conditions and diseases.
research Comparative Management Methods for Adolescents With Polycystic Ovarian Syndrome: A Systematic Review
Individualized treatment plans, including lifestyle changes and specific medications, are crucial for managing PCOS in adolescents.
research Trichoblastoma with Sebaceous and Sweat Gland Differentiation
A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.
research Mechanistic Synergy of Hair Growth Promotion by the Avicennia Marina Extract and Its Active Constituent Avicequinone C in Dermal Papilla Cells Isolated From Androgenic Alopecia Patients
Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.
research Telogen Effluvium as the First Symptom of Crohn's Disease in a Child
Hair loss in a child was an early sign of Crohn's disease.
research Caffeic Acid N-[3,5-Bis(Trifluoromethyl)Phenyl] Amide as a Non-Steroidal Inhibitor for Steroid 5α-Reductase Type 1 Using a Human Keratinocyte Cell-Based Assay and Molecular Dynamics
Compound 4 is a promising treatment for hair loss with low toxicity.
research Intracrinology and the Skin
DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
research Polygonum Multiflorum Extract Supports Hair Growth by Elongating Anagen Phase and Abrogating the Effect of Androgen in Cultured Human Dermal Papilla Cells
Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.
research Telomere Dynamics and Telomerase in the Biology of Hair Follicles and Their Stem Cells as a Model for Aging Research
Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
research A Comparative Study of Materials Assembled from Recombinant K31 and K81 and Extracted Human Hair Keratins
Recombinant keratin materials may better promote skin cell differentiation than natural keratin.
research A Study of the Clinical Patterns of Hair Loss in Female Patients
Most women aged 20-40 in the study lost hair diffusely and in volume over 6 weeks to 6 months, mainly due to telogen effluvium, often without a clear cause.
research Endocrinology
The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
research Copper-Doxorubicin as a Nanoparticle Cargo Retains Efficacy with Minimal Toxicity
Copper-doxorubicin nanoparticles effectively treat tumors with less toxicity.
research Clinical Application of Nonantibiotic Macrolides for Inflammation-Driven Immune Dysfunction in Inflammatory Skin Diseases
Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.