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Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.

Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Platelet-Rich Plasma (PRP) shows promise for treating various skin conditions, but more research is needed to standardize its use.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Polycystic Ovary Syndrome can cause hair loss and skin issues, and early treatment is important for preventing complications.

All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Nanotechnology improves minoxidil treatment for hair loss.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Family members of North Indian women with PCOS have a high rate of metabolic syndrome.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

The 2018 update to the ED care model added a new severity score and stressed a detailed evaluation of both physical and psychological aspects.

Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.