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Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

RT1640 treatment reverses gray hair and promotes hair growth in mice.

Laminin-511 may contribute to psoriasis by affecting skin cell growth and survival.

Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.

Birth control pills and anti-androgen medications help manage hair growth, acne, and hair loss in women with PCOS.

IL-33 is linked to hair follicle damage in psoriasis and could be a treatment target for hair loss in this condition.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Mycophenolate helps reverse hair loss effects caused by IFN-γ by activating a key hair growth pathway.

Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.

Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.

PCOS is a common hormonal disorder with symptoms like irregular periods and excess hair growth, managed with lifestyle changes and medications.

Cucurbitacin helps mice grow hair by blocking a protein that stops hair growth.

Exosomes from dermal papilla cells help hair follicle stem cells grow and survive.

TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Platelet-rich plasma can help grow more mouse hair follicles, but it doesn't work for human hair follicles yet.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

Certain growth factors significantly affect hair loss in women with telogen effluvium.

Both main and alternative Wnt signaling are important for regrowing rodent whisker follicles.

Hair follicle cells help maintain and support stem cells and blood cell formation.

Ganoderma lucidum extract may help treat stress-related hair loss.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Different types of stem cells and their environments are key to skin repair and maintenance.