research Characterization of CD4+ Stem Cells of the Skin and Their Role in Skin Homeostasis and Tumorigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
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research Differential Expression of Stem Cell Markers in Human Follicular Bulge and Interfollicular Epidermal Compartments
Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
research Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation
Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
research What's New in Cicatricial Alopecia?
New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.
research Genetically Modified Laboratory Mice with Sebaceous Glands Abnormalities
Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.
research Lactate Dehydrogenase Activity Drives Hair Follicle Stem Cell Activation
Lactate production is important for activating hair growth stem cells.
research The Role of PPARγ-Mediated Signalling in Skin Biology and Pathology: New Targets and Opportunities for Clinical Dermatology
PPARγ is crucial for skin health but can have both beneficial and harmful effects.
research Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells
Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
research External Light Activates Hair Follicle Stem Cells Through Eyes Via an ipRGC–SCN–Sympathetic Neural Pathway
Light can turn on hair growth cells through a nerve path starting in the eyes.
research In Vitro Identification of a Stem Cell Population from Canine Hair Follicle Bulge Region
Researchers found stem cells in dog hair follicles using specific markers.
research Long-Term Expansion and Differentiation of Adult Murine Epidermal Stem Cells in 3D Organoid Cultures
A new 3D culture system helps grow and study mouse skin stem cells for a long time.
research Wound-Induced Hair Neogenesis: A Novel Paradigm for Studying Regeneration and Aging
Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
research In Vivo Transcriptional Governance of Hair Follicle Stem Cells by Canonical Wnt Regulators
Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
research Stem Cell Dynamics in the Hair Follicle Niche
Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
research Keratin 79 Identifies a Novel Population of Migratory Epithelial Cells That Initiates Hair Canal Morphogenesis and Regeneration
Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.
research The Therapeutic Promise of Apoptosis
Blocking cell death in certain stem cells can improve wound healing and tissue regeneration.
research A Matter of Life and Death: Self-Renewal in Stem Cells
Stem cell self-renewal is complex and needs more research for full understanding.
research Alopecia: Evaluation and Treatment
The document concludes that proper diagnosis and FDA-approved treatments for different types of hair loss exist, but treatments for severe cases often fail and future improvements may focus on hair follicle stem cells.
research Runx Family Genes in Tissue Stem Cell Dynamics
Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
research Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells
Men with baldness due to androgenetic alopecia still have hair stem cells, but lack specific cells needed for hair growth.
research Multipotent Nestin-Expressing Hair Follicle Stem Cells
Hair follicle stem cells can turn into various cell types and help repair nerves.
research Next Generation Human Skin Constructs as Advanced Tools for Drug Development
Advanced human skin models improve drug development and could replace animal testing.
research The Vitamin D Receptor Is Required for Mouse Hair Cycle Progression but Not for Maintenance of the Epidermal Stem Cell Compartment
Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.
research Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling
Fat-related cells are important for initiating hair growth.
research Cutaneous Epithelial Stem Cells
Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
research Genetically-Manipulated Adult Stem Cells as Therapeutic Agents and Gene Delivery Vehicles for Wound Repair and Regeneration
Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
research Skin Biology
Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
research Ferreting Out Stem Cells From Their Niches
New methods have greatly improved our understanding of stem cell behavior and roles in the body.
research Thymic Stromal Lymphopoietin Controls Hair Growth
Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.
research Cell Therapy for Androgenetic Alopecia: Elixir or Trick?
Stem cell therapies could be a promising alternative for hair loss treatment, but more research is needed to understand their full potential and safety.