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    Glossary Scalp Cooling

    reduces hair loss during chemotherapy by cooling the scalp

    Scalp Cooling, also known as Cold Cap Therapy or Scalp Hypothermia, is a technique used to reduce hair loss during chemotherapy. It involves wearing a specially designed cap filled with a cooling agent before, during, and after chemotherapy sessions. The cooling effect constricts blood vessels in the scalp, reducing the amount of chemotherapy drugs that reach hair follicles, thereby minimizing hair loss.

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    1. 化療掉髮:頭皮冷凍帽(scalp cooling)真的有效嗎? Open MIND · 2026
    2. Scalp Cooling Methods for Chemotherapy-Induced Hair Loss: A Comprehensive Review from Traditional Practices to Modern Innovations 2025
    3. Simulation of scalp cooling by external devices for prevention of chemotherapy-induced alopecia Journal of thermal biology · 2015 · 7 citations
    4. 50524 Facebook groups provide support and product recommendations for patients using scalp cooling to prevent chemotherapy-induced alopecia: A survey study Journal of the American Academy of Dermatology · 2024
    5. Management of Chemotherapy-Induced Alopecia With Scalp Cooling Journal of oncology practice · 2018 · 25 citations
    6. Alopecia, quimioterapia y gorras de frío o «scalp cooling system» Actas Dermo-Sifiliográficas · 2021 · 13 citations
    7. [Translated article] Chemotherapy, Alopecia, and Scalp Cooling Systems Actas Dermo-Sifiliográficas · 2022 · 6 citations
    8. 1400 Low-intensity ultrasound protects human scalp hair follicles from taxane-induced toxicity 2023
    9. Efficacy of Scalp Cooling System Versus Chemical Cooling Cap in Preventing Chemotherapy-induced Alopecia in Breast Cancer (COHAIR Study): a prospective randomized trial The Breast · 2026
    10. Hair disorders in patients with cancer Journal of The American Academy of Dermatology · 2018 · 53 citations
    11. ISID1403 - Melatonin protects K15+ human hair follicle stem cells against paclitaxel-induced damage ex vivo 2023
    12. Innovations for cost-effective and eco-friendly solutions to combat chemotherapy-induced alopecia: a narrative systematic review Supportive Care in Cancer · 2026
    13. Chemotherapy-induced alopecia Current Opinion in Supportive and Palliative Care · 2010 · 44 citations
    14. Cold thermal injury from cold caps used for the prevention of chemotherapy-induced alopecia Breast cancer research and treatment · 2016 · 22 citations
    15. 1403 Melatonin protects K15+ human hair follicle stem cells against paclitaxel-induced damage ex vivo Journal of Investigative Dermatology · 2023
    16. The Influence of Various Parameters on the Success of Sensor-Controlled Scalp Cooling in Preventing Chemotherapy-Induced Alopecia Oncology Research and Treatment · 2015 · 21 citations
    17. Persistent major alopecia following adjuvant docetaxel for breast cancer: incidence, characteristics, and prevention with scalp cooling Breast Cancer Research and Treatment · 2018 · 19 citations
    18. The efficacy of scalp-cooling system for the prevention of chemotherapy-induced hair loss in metastatic breast cancer patients treated with eribulin Annals of oncology · 2018
    19. Scalp cooling has no place in the prevention of alopecia in adjuvant chemotherapy for breast cancer European Journal of Cancer · 1994 · 39 citations
    20. Characterization of the role of Facebook groups for patients who use scalp cooling therapy: a survey study Supportive Care in Cancer · 2024 · 4 citations
    21. Presentation, impact and prevention of chemotherapy-induced hair loss: scalp cooling potentials and limitations Expert review of dermatology · 2011 · 62 citations
    22. Efficacy and tolerability of two scalp cooling systems for the prevention of alopecia associated with docetaxel treatment Supportive Care in Cancer · 2013 · 52 citations
    23. Efficacy and tolerability of scalp cooling in preventing alopecia during (neo)adjuvant chemotherapy for breast cancer Pathology & Oncology Research · 2026
    24. The efficacy of scalp cooling in patients receiving chemotherapy for primary gynecologic cancers: a randomized controlled trial Scientific Reports · 2026
    25. Formulation and characterisation of resveratrol-loaded nanostructured lipid carriers for use in combination with scalp cooling therapy to mitigate chemotherapy-induced follicular cytotoxicity and hair loss Journal of Drug Delivery Science and Technology · 2025
    26. Scalp cooling to prevent chemotherapy-induced alopecia 2020 · 17 citations
    27. Improving Quality of Life During Chemotherapy: Cannabinoids, Cryotherapy, and Scalp Cooling American Society of Clinical Oncology Educational Book · 2023 · 6 citations
    28. Expanding the Availability of Scalp Cooling to All Patients at Risk of Chemotherapy-Induced Alopecia Journal of Market Access & Health Policy · 2024 · 5 citations
    29. Scalp cooling versus standard cold-cap in preventing chemotherapy-induced alopecia in patients with localized breast cancer: ICELAND protocol, a randomized controlled trial and economic evaluation PLoS ONE · 2026
    30. Low-Intensity Ultrasound as a Potential Intervention Strategy to Protect Human Scalp Hair Follicles from Taxane-Induced Toxicity Journal of Investigative Dermatology · 2023 · 7 citations