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Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

Vitamin D receptor is crucial for starting hair growth after birth.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.

Some drugs may reduce prostatitis symptoms short-term with few side effects.

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Minoxidil effectively regrows hair in male pattern baldness.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Finasteride works better than Serenoa repens for male hair loss.

About 13% of women had idiopathic hirsutism and 8.5% had polycystic ovary syndrome in a group of Iranian women.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

South Asian women with PCOS experience more psychological distress and have a poorer quality of life, especially in social relationships, with hirsutism affecting them more than obesity.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.