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Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

Aromatase gene variation may increase female hair loss risk.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

The conclusion is that certain scalp tissue changes are characteristic of lichen planopilaris, with mucinous perifollicular fibroplasia being a new feature for diagnosis.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Certain mice without specific receptors or mast cells don't lose hair from stress.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.

Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.

Papain and bisulfite break down human hair by dissolving parts of it.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.

Men who think they are losing hair feel worse about themselves, especially if they are younger.

Toxic epidermal necrolysis is a severe skin condition often caused by drugs, with complex treatment and a high risk of death, but survivors usually heal without scars.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

The document concludes that accurate diagnosis of hair disorders is crucial and requires a range of diagnostic methods.

Prolactin affects when mice shed and grow hair.

Lasers and light sources can effectively remove hair, work best on fair skin with dark hair, and usually need multiple treatments.

Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.

The document says to treat cat fungal infections with medicine and clean the environment, noting that cats without symptoms can still spread it to humans.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Anti-TNF therapy can cause a unique type of hair loss that may get better with topical treatments without stopping the therapy.

Finasteride can slow hair loss and promote growth in postmenopausal women.

Frequent hair coloring and styling can damage hair and cause breakage or loss.