2 citations
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July 2023 in “Agronomy” This study found that treating wheat with 100 µM melatonin under drought conditions significantly improved root and shoot growth, increased melatonin levels, and enhanced drought resistance, potentially clarifying the mechanisms of melatonin's protective effects in plants facing water scarcity.
In this study of hydroponically grown tomatoes, the authors reported that adding melatonin at 10-30 μmol·L-1 effectively enhanced lateral root development, root hair growth, biomass accumulation, and root activity by influencing related gene expression and hormone levels.
95 citations
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July 2007 in “Journal of Experimental Botany” This study found that the superior growth and higher zinc uptake of wild-type barley compared to its root-hairless mutant in zinc-deficient soil is mainly due to greater root surface area from root hairs.
2 citations
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September 2025 in “BMC Genomics” This study found that maize root hairs respond differently to cold stress based on severity, with mild cold allowing limited growth through adaptive remodeling, while severe cold causes more pronounced inhibition and prioritizes stress defense, affecting transcriptome and morphology.
June 2026 in “New Phytologist” This study used multi-omics analysis to explore how wheat roots adapt to temperature stress, revealing that distinct hormonal signaling pathways are linked to iron homeostasis and drive root morphological changes, supporting the idea of an 'iron-dependent hormonal trade-off' model.
30 citations
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July 2021 in “Annals of Botany” This study observed that maize plants enhance phosphorus acquisition by promoting both root hair growth and lateral root development in response to localized nutrient patches, highlighting a complementary root trait trade-off.
12 citations
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July 1993 in “In Vitro Cellular & Developmental Biology - Animal” Minoxidil enhances hair growth and preserves the root sheath in cultured follicles.
January 2014 in “Journal of the Korean Society of Design Culture” This study found that in female patients with telogen effluvium, club hair in the isthmus region was longer than in those with alopecia areata, offering insights into hair morphology differences.
11 citations
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February 1982 in “RePub (Erasmus University, Rotterdam)” This review discusses the evolution of hair plucking techniques for diagnosing hair disorders and suggests uniform methods could improve consistency in evaluating hair growth and treatment.
December 2023 in “International Journal of Medical Arts” In this study, researchers observed significant morphological and histological differences in transplanted hair follicles compared to native donor follicles post-FUE hair transplantation for androgenetic alopecia, highlighting substantial variations in sebaceous gland and root sheath degeneration at the recipient site.
47 citations
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July 1967 in “Science” This study observed morphological changes in scalp hair follicles of humans deprived of protein for 15 days, which suggests potential use in diagnosing protein-calorie malnutrition.
8 citations
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September 1981 in “Zentralblatt für Veterinärmedizin Reihe A” In this animal study, pigs on a biotin-deficient diet showed significant hair loss, weak and brittle claws, and skin lesions after 8–10 weeks, with tissue necrosis observed microscopically after 15 weeks.
4 citations
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January 1976 in “Archives of Dermatological Research” Metabolic disorders can cause hair structure defects and growth issues, but amino acid levels in hair remain normal.
1 citations
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July 2017 in “Microscopy and Microanalysis” In this study using C57BL/6 mice, researchers found that iron oxide nanoparticles permeated skin primarily through hair follicles and sebocytes, with absorption increasing over time.
In this study, Sox13 was identified as a novel marker for early hair follicle development and differentiation in mice, though it appears to be dispensable for overall epidermal and adnexal development.
94 citations
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February 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” This study concluded that epidermal growth factor may induce a 'catagen-like' phase in human hair follicles by disrupting normal cellular proliferation and migration patterns.
63 citations
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July 2006 in “British Journal of Dermatology” This study found that keratin K17 is induced in the suprabasal layer of psoriatic scalp epidermis during epidermal hyperproliferation, suggesting it is not specific to hair follicles.
51 citations
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May 1984 in “Journal of the American Academy of Dermatology” In this study, the authors observed that cell-mediated immune mechanisms may be involved in the pathogenesis of benign follicular mucinosis, based on the cellular and immunological characteristics of two patient cases.
23 citations
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July 1994 in “Journal of Dermatological Science” This study found that the twisted hair shafts characteristic of pili torti may result from uneven outer root sheath cell development, leading to irregular hair shaft modeling and twisting.
6 citations
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August 1985 in “Archives of dermatology” In this study, two cases of idiopathic hair casts in young girls responded well to 0.025% tretinoin lotion, with analyses suggesting an infrainfundibular origin for the lesions.
This study explored chitosan-based dissolving microneedle arrays loaded with Agave tequilana root extract, finding that extract concentration influenced microneedle geometry and bioactivity, maintaining antioxidant and enzyme inhibitory effects while reducing collagenase inhibition, particularly in the 0.25% formulation.
January 2014 in “Journal of Pharmaceutical Negative Results” This study found that the ethanolic extracts of G. glabra and Z. mauritiana roots did not prevent androgenic alopecia in a testosterone-induced animal model.
20 citations
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November 1968 in “The Lancet” This study found that during dialysis, lower plasma-potassium levels were associated with hyperglycemia, suggesting potassium correction is vital when using glucose-rich dialysate.
149 citations
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June 2010 in “The FASEB journal” In this study, miR-31 was found to play a significant role in hair cycle regulation in mice by controlling key gene expressions involved in hair growth and differentiation.
This study found that culturing hair follicles at the air-liquid interface enhanced hair growth and maintained an anagen-like morphology better than submerged cultures.
1 citations
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June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that in wild-type Arabidopsis plants, root hair growth is suppressed with increased nutrient availability, with RHD6 subfamily genes down-regulated and GTL1 and DF1 genes influencing root hair morphology under these conditions.
This study analyzed inner root sheath-specific genes in Tan sheep during various growth stages, finding peak expression at birth. The pattern of genes KRT71, KRT72, and TCHH is consistent with wool crimp, potentially influencing wool morphology.
78 citations
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May 2018 in “Plant Soil and Environment” This study found that inoculating tea plants with arbuscular mycorrhizal fungi significantly improved growth, root morphology, and leaf nutrient levels, with Claroideoglomus etunicatum showing the most substantial effects.
April 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” This study introduced the dual-flow-RootChip platform to demonstrate that Arabidopsis roots exhibit non-autonomous adaptations, such as hair growth regulation, when subjected to varied environmental conditions on opposite sides.
4 citations
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January 2019 in “Micron” This study observed that fetal hair follicle melanocytes varied in morphology and development stages, with melanosomes undergoing degradation into irregular pigment particles within keratinocytes.