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GlossaryDorsal Root Ganglia

clusters of nerve cell bodies transmitting sensory information to the spinal cord

Dorsal Root Ganglia (DRG) are clusters of nerve cell bodies located along the spinal cord. They play a crucial role in transmitting sensory information from the peripheral nervous system to the central nervous system, including sensations like pain, temperature, and touch.

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Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways

research Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways

66 citations, July 2007 in “Journal of Molecular Medicine”

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

research KCNQ Potassium Channels Modulate Sensitivity of Skin Down-Hair (D-Hair) Mechanoreceptors

19 citations, February 2016 in “Journal of Biological Chemistry”

KCNQ potassium channels help control the sensitivity of touch receptors in the skin.

ELife Assessment: Touch Receptor End-Organ Innervation and Function Require Sensory Neuron Expression of the Transcription Factor Meis2

research ELife Assessment: Touch Receptor End-Organ Innervation and Function Require Sensory Neuron Expression of the Transcription Factor Meis2

February 2024

Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.

Local Injection With Anti-Herpes Simplex Virus Antibodies Protects Against Development of Herpes Simplex Virus-Induced Sweating Disturbance

research Local Injection With Anti-Herpes Simplex Virus Antibodies Protects Against Development of Herpes Simplex Virus-Induced Sweating Disturbance

April 2023 in “Journal of Investigative Dermatology”

Injecting anti-herpes antibodies locally can prevent skin lesions and sweating problems caused by herpes simplex virus in mice.

research Tfap2b Specifies an Embryonic Melanocyte Stem Cell That Retains Adult Multi-Fate Potential

June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.

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community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 71 upvotes 4 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community How to know if shedding is from tren or minoxidil?

in Minoxidil 5 upvotes 7 months ago

The user started using trenbolone and minoxidil simultaneously and experienced increased hair shedding, unsure which is causing it. Replies suggest both drugs could cause hair loss, with one advising to stop trenbolone to protect hair and another indicating minoxidil is unlikely the cause due to the timing.