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GlossaryDorsal Root Ganglia

clusters of nerve cell bodies transmitting sensory information to the spinal cord

Dorsal Root Ganglia (DRG) are clusters of nerve cell bodies located along the spinal cord. They play a crucial role in transmitting sensory information from the peripheral nervous system to the central nervous system, including sensations like pain, temperature, and touch.

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Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways

research Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways

66 citations , July 2007 in “Journal of Molecular Medicine”

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

research Localization of Mechanosensitive Channel TRPV4 in Mouse Skin

123 citations , November 2003 in “Neuroscience Letters”

TRPV4 helps sense pressure in mouse skin.

research KCNQ Potassium Channels Modulate Sensitivity of Skin Down-Hair (D-Hair) Mechanoreceptors

19 citations , February 2016 in “Journal of Biological Chemistry”

KCNQ potassium channels help control the sensitivity of touch receptors in the skin.

research Different Requirements for GFRα2 Signaling in Three Populations of Cutaneous Sensory Neurons

11 citations , August 2014 in “PLoS ONE”

GFRα2 is essential for controlling neuron size but not for target innervation in certain sensory neurons.

ELife Assessment: Touch Receptor End-Organ Innervation and Function Require Sensory Neuron Expression of the Transcription Factor Meis2

research ELife Assessment: Touch Receptor End-Organ Innervation and Function Require Sensory Neuron Expression of the Transcription Factor Meis2

February 2024

Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.

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