Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses advanced techniques for investigating stem cell fate at the single-cell level, including lineage tracing, time-lapse imaging, and molecular profiling, but reports no new research results.

This study found that maternal PPARγ is essential for preventing the production of inflammatory lipids in mouse milk, which can otherwise cause inflammation, alopecia, and growth retardation in nursing pups.

In this study, a novel mutation in the glucocorticoid receptor gene was identified in a young woman, impairing glucocorticoid signaling and leading to generalized glucocorticoid resistance.

In this study, specific versican expression was observed in the anagen phase of human hair follicles, suggesting its importance in maintaining normal hair growth.

This study found that mouse skin can produce and metabolize serotonin and N-acetylserotonin, with activity influenced by location, physiological skin status, cell type, and mouse strain.

This study found that stimulating the olfactory receptor OR2AT4 in human hair follicles with a synthetic sandalwood odorant promotes hair growth ex vivo by decreasing apoptosis and increasing IGF-1 production.

This study found that silencing clock genes BMAL1 or PER1 in human hair follicles increased melanin content and melanocyte activity, suggesting these genes influence pigmentation.

In this study, researchers found that exposure to PM10 significantly increased inflammation and impaired collagen synthesis in human dermal fibroblasts, suggesting PM10 contributes to skin aging through these mechanisms.

This study demonstrates that inhibiting SFRP1 with the antagonist WAY-316606 enhances hair growth in human scalp hair follicles ex vivo by facilitating Wnt signalling.

This study found that in vivo, a novel microneedle system for valproic acid delivery may improve hair regrowth efficacy by upregulating hair follicle development pathways more effectively than topical application.

This study found that PGD2 inhibits hair follicle regeneration in mice through the Gpr44 receptor, suggesting that blocking PGD2 or Gpr44 may enhance skin regeneration after wounds.

This study found that a 70% methanol extract from red ginseng stimulated hair growth in mouse vibrissal follicles, suggesting its bioactive components, particularly certain ginsenosides, may promote hair growth.

This study found that bimatoprost stimulated hair growth in both human scalp follicle cultures and mouse pelage in vivo, suggesting it might offer a promising treatment for scalp alopecias.

The study found that severe insulin resistance and premature diabetes are common in patients with PCNT genetic defects, primarily affecting those over four years old, while not impacting early insulin signaling in adipocytes.

This study highlights that the mammalian target of rapamycin complex 2 (mTORC2)-Akt signaling axis is essential for hair follicle stem cells to return to their niche and regenerate effectively by regulating metabolic pathways.

In this study, red ginseng extract and its ginsenosides enhanced human hair follicle cell proliferation and countered dihydrotestosterone-induced suppression, suggesting potential to promote hair growth.

This review assesses the current literature on COVID-19's effects on male sexual and reproductive health, highlighting significant research gaps and providing guidance for patient counseling.

In this study, decreased expression of BMP2 and ephrin A3 and increased NT-4 gene expression were observed in dermal papilla cells from androgenic alopecia-affected skin, suggesting potential roles in hair growth regulation.

This study found that androgen receptor activation in adult mouse skin reduces β-catenin-induced hair follicle growth and sebaceous gland conversion, highlighting its role in stem cell fate decisions.

This study found that the Wnt/β-catenin signaling pathway activates melanocyte stem cells, promoting hair follicle regeneration both in vitro and in vivo.

This study found that a eupafolin nanoparticle delivery system improved water solubility and skin penetration, enhancing its antioxidant and anti-inflammatory effects against particulate matter-induced stress in skin cells.

This study found that deleting Stim1 and Stim2 in mature T regulatory cells disrupts Ca 2+ signaling, preventing their differentiation and leading to severe autoimmune disorders in mice.

Raspberry ketone may help grow hair and improve skin elasticity.

This study found that overexpressing PLC5 in Arabidopsis thaliana reduced root growth but improved drought tolerance, and suggests PIP2 is crucial for root hair growth.

This study found that platelet-derived growth factor signaling is crucial for maintaining the hair follicle dermal stem cell pool and supporting their regenerative capacity.

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

This study found that white hair exhibits increased expression of genes and proteins linked to active hair growth compared to black hair, suggesting that hair greying is associated with enhanced hair growth activity.

This study found that fibromodulin significantly reduces scar formation and boosts scar strength in rodent and porcine models, suggesting potential for FMOD-based therapies in cutaneous wound repair.

In this study, researchers found that alkylating chemotherapy causes hair follicle stem cells to lose their regenerative ability by initially triggering proliferation followed by apoptosis, leading to permanent regeneration loss.

This study observed that CIP/KIP proteins play a significant role in regulating cell cycle arrest and differentiation in human hair follicles, supporting hair growth and formation in the anagen phase.