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The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Growing human skin cells in a 3D environment can stimulate new hair growth.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

The Rotterdam Study aims to understand various diseases in older adults.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

PGD2 stops hair growth and is higher in bald men with AGA.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

A patient with Alopecia Areata had complete hair regrowth after using the drug baricitinib.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.