51 citations
,
July 2013 in “Brain Research” Testosterone needs to be converted to DHT to reduce stress response in male rats.
31 citations
,
July 2012 in “Journal of Lipid Research” This study found that the acyl-CoA binding protein is essential for the production of very long chain free fatty acids in the stratum corneum and maintaining normal epidermal barrier function in mice.
29 citations
,
July 2014 in “PloS one” In this study, Meis1 was found to regulate epidermal homeostasis and act as a proto-oncogenic factor in skin tissues, with differences in expression patterns between normal and tumor cells.
29 citations
,
July 2014 in “PLoS ONE” This study suggests that inactivation of β-catenin is necessary for chick retina regeneration, as it allows cells to enter the cell cycle during injury and promotes regeneration without needing FGF2.
26 citations
,
September 2012 in “Cell Reports” In this study, knockout of B-raf and C-raf genes in mice showed they are not needed for early melanocyte development, but are crucial for maintaining melanocyte stem cells, as evidenced by hair graying due to stem cell depletion.
25 citations
,
November 2018 in “Cell reports” This study found that the ablation of Esrp1 and Esrp2 disrupts epithelial tight junctions by affecting Arhgef11 isoform expressions, highlighting a potential mechanistic link between splicing alterations and epithelial barrier defects.
25 citations
,
March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that while VDR is crucial for maintaining hair follicles in mice, their degeneration may be linked to impaired cell migration during hair growth phases rather than stem cell loss.
21 citations
,
February 2023 in “Bioengineering” This review outlines current European legislation and manufacturing standards for platelet-rich plasma (PRP) products and provides guidance for clinicians implementing autologous PRP treatments, without reporting new clinical results.
19 citations
,
August 2022 in “Plant Signaling & Behavior” This article reviews how calcium and reactive oxygen species gradients and oscillations interact to promote root hair cell expansion and reports no new experimental findings.
18 citations
,
February 2006 in “Brain & development” This case study reports successful treatment of a 19-year-old with Satoyoshi syndrome using a combination of carbamazepine, methotrexate, prednisolone, and sex-steroids, improving muscle spasms, alopecia, and quality of life.
15 citations
,
February 2014 in “Journal of Investigative Dermatology” NF-κB activity is crucial for keeping hair in the growth phase.
12 citations
,
March 2021 in “Journal of Investigative Dermatology” TRPM5 is crucial for maintaining hair growth.
12 citations
,
October 2017 in “Radiation Research” This study observed that mTORC1 signaling is activated and crucial for hair follicle regeneration and hair growth in irradiated mice, facilitating recovery within 96 hours without significant hair loss.
8 citations
,
August 2018 in “Journal of Investigative Dermatology”
5 citations
,
September 2000 in “Dermatologic Surgery” This study suggests that dividing the face into thirds may guide hairline development during follicular transplantation for men with type III-V male pattern baldness.
3 citations
,
March 2024 in “Viruses” This study found that γδ T cells in the skin contribute to wound healing after vaccinia virus infection by promoting cytokine and growth factor induction, without affecting virus replication control.
1 citations
,
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that skin-resident and recruited γδ T cells play a crucial role in an early wound healing response following cutaneous vaccinia virus infection, rather than in controlling virus replication.
1 citations
,
August 2009 in “Mechanisms of Development”
December 2025 in “International Journal of Newgen Research in Pharmacy & Healthcare” This review compares regulations for herbal hair products' labeling and claim validation across various regions, identifying existing discrepancies and discussing the need for global standardization to improve consumer protection and trade facilitation.
This study discovered that in *Drosophila*, knockdown of specific storage proteins in adipocytes decreased germline stem cell maintenance, implicating a role for these proteins in adult tissue regulation.
The researchers observed that in cases of alopecia areata with atypical features, histopathological confirmation may be necessary, as trichoscopic clues like loss of follicle ostia and vellus hairs were common, while typical features such as exclamation mark hairs were not always present.
December 2023 in “Frontiers in plant physiology” This review discusses recent findings on how root hairs and root exudate secretion play critical roles in recruiting nitrogen-fixing bacteria, potentially aiding the development of cereal crops that can use atmospheric nitrogen, which may reduce reliance on synthetic fertilizers.
February 2023 in “American Journal of Biomedical and Life Sciences” The researchers reported that hair bio element median derivatives bioassay is an effective and reliable method for evaluating the nutritional status of various bio elements, offering a non-invasive approach for nutritional health surveillance and precision medicine.
July 2022 in “Journal of Investigative Dermatology” This study found that Dkk4-knockout mice exhibited disrupted hair follicle patterning, including a lack of the first wave of hair follicles in the lateral back skin.
October 2021 in “Journal of Investigative Dermatology” This study reported that Dkk4-knockout mice showed disrupted hair follicle patterning, suggesting a WNT-DKK axis may influence regional specificities in hair follicle induction related to androgenetic alopecia.
January 2020 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” This study found that Polycomb Repressive Complex 1 is crucial for maintaining stem cell identity across different lineages, but its loss results in varied transcriptional outcomes depending on the tissue context.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, mouse sebaceous glands were found to require nerves for growth during active hair cycles, suggesting a nerve-dependent sebaceous gland cycle coordinated with hair growth.
April 2016 in “Journal of Investigative Dermatology” The authors concluded that Wnt ligands produced by hair-inducing dermal papilla cells have crucial roles in coordinating postnatal hair growth by interacting with both epithelial and mesenchymal compartments.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Iron deficiency is not more common in women with hair loss, and neurogenic rosacea may need different treatment.
April 2010 in “The journal of immunology/The Journal of immunology” This study found that deleting the FoxN1 gene in mice disrupted the 3D thymic epithelial structure and led to 2D epithelial cysts, revealing its crucial role in thymus organization but not causing athymia.