research Central Centrifugal Cicatricial Alopecia
CCCA is a scarring hair loss condition mainly in African descent women, possibly caused by genetics and hairstyling, treated with gentle hair care and medications.
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510-540 / 1000+ results research Dermatitis as a Presenting Sign of Cystic Fibrosis
Recognizing certain rashes can lead to earlier cystic fibrosis diagnosis and better outcomes.
research Inborn Errors of Biotin Metabolism
Two enzyme defects in biotin metabolism cause severe skin, hair, and metabolic issues.
research Overlooked Non-Motor Symptoms in Myasthenia Gravis
Non-motor symptoms in myasthenia gravis are common and need early diagnosis for better management.
research Skin Disorders in Parkinson’s Disease: Potential Biomarkers and Risk Factors
Certain skin conditions may indicate or increase the risk of Parkinson's disease.
research Updates in Therapeutics for Folliculitis Decalvans: A Systematic Review with Evidence-Based Analysis
Clindamycin and rifampicin are the most effective treatments for folliculitis decalvans, but more research is needed.
research Novel De Novo Pathogenic Variant in the ODC1 Gene in a Girl with Developmental Delay, Alopecia, and Dysmorphic Features
A 32-month-old Caucasian female was identified with a heterozygous de novo nonsense mutation in the ODC1 gene, leading to a new pediatric disorder characterized by developmental delay, alopecia, and other symptoms such as macrosomia and macrocephaly. This mutation resulted in elevated ODC protein and polyamine levels in red blood cells. The case confirmed similar symptoms observed in a transgenic ODC1 mouse model. The mutation was identified through whole-exome sequencing and confirmed by Sanger sequencing. The patient might benefit from treatment with α-difluoromethylornithine, an FDA-approved drug.
research Template-Directed Self-Assembly and Growth of Insulin Amyloid Fibrils
A new method speeds up insulin amyloid fibril growth, useful for studying diseases.
research Hematological And Hepatic Effects Of Vascular Epidermal Growth Factor (VEGF) Used To Stimulate Hair Growth In An Animal Model
VEGF gel increases hair growth but may have potential toxicity.
research Dermatological Manifestations Associated with COVID-19: A Comprehensive Review of the Current Knowledge
COVID-19 can cause various skin issues, including rashes and hair loss, which usually heal on their own and don't always indicate severe illness.
research Human Skin Color: Origin, Variation, and Significance
Human skin and hair color variation is mainly due to melanin produced by a few genes, with melanin protecting against sun damage.
research Reduced Serum Vitamin B12 Levels During Oral Cyproterone Acetate and Ethinyl Estradiol Therapy in Women With Diffuse Androgen-Dependent Alopecia
Taking cyproterone acetate and ethinyl oestradiol for hair loss can lower vitamin B12 levels in women.
research Benign Prostatic Hyperplasia And Male Lower Urinary Symptoms: A Guide For Family Physicians
Family doctors can manage older men with urinary symptoms using exams, tests, and medications.
research De Novo Mutation in the Mitochondrial tRNA Leu(UUR) Gene (A3243G) with Rapid Segregation Resulting in MELAS in the Offspring
A new mutation in the mitochondrial DNA was found in a boy with MELAS, even though his family didn't show typical signs.
research A Stain for Plucked Anagen Hairs
A new staining method helps tell growing from resting hairs to diagnose hair loss.
research Biochemical Features of Primary Cells from a Pediatric Patient with a Gain-of-Function ODC1 Genetic Mutation
A new genetic disorder caused by an ODC1 mutation can be treated with DFMO.
research Discoid Lupus Erythematosus Exacerbated by Contact Dermatitis Caused by Use of Squaric Acid Dibutylester for Topical Immunotherapy in a Patient with Alopecia Areata
Topical squaric acid dibutylester worsened discoid lupus erythematosus in a patient.
research Structure Optimization of Tetrahydropyridoindole-Based Aldose Reductase Inhibitors Improved Their Efficacy and Selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research Oxidative Stress in Androgenetic Alopecia
People with a common type of hair loss have higher stress levels in their body, and treatments that reduce this stress could help.
research Anti-Grey Hair Vitamin Deficiency in the Silver Fox
Lack of certain vitamins causes fur loss and greying in silver foxes.
research Development and Evaluation of Antisense shRNA-Encoding Plasmid Loaded Solid Lipid Nanoparticles Against 5-Alpha Reductase Activity
The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
research Controversy: Is There a Role for Adjuvants in the Management of Male Pattern Hair Loss?
Adjuvants, diet changes, and laser therapy may improve male pattern hair loss.
research Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors and Antioxidants as Promising Drugs for the Treatment of Diabetic Complications
New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.
research How Different Is Human Hair? A Critical Appraisal of Global Hair Fibre Characteristics and Properties Towards Defining a More Relevant Framework for Hair Type Classification
Human hair varies widely and should be classified by curl type rather than race.
research Pleomorphic Appearance of Breast Cancer Cutaneous Metastases
Breast cancer skin metastases are rare, look different, and can be confused with other skin issues, so a biopsy is needed for accurate diagnosis.
research Tinea Capitis Due to Trichophyton Soudanense
A 6-year-old girl in the U.S. had a rare scalp infection caused by *Trichophyton soudanense*.
research Predicting Human Appearance from DNA for Forensic Investigations
DNA can predict physical traits like eye and hair color accurately, especially in Europeans, but predicting other traits and in diverse populations needs more research.
research Case 7-2015
The conclusion of the case is not provided in the summary.
research Keloid Scars Arising After Follicular Unit Extraction Hair Transplantation
Keloid scars can form after hair transplant surgery and should be prevented and treated early.
research Ishige Sinicola Extract Stimulates Osteoblast Proliferation and Differentiation via the Bone Morphogenetic Protein 2/Runt-Related Gene 2 Signaling Pathway
Ishige sinicola extract helps bone-building cells grow and mature, which could aid in treating osteoporosis.