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Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

A patient with Alopecia Areata had complete hair regrowth after using the drug baricitinib.

Trichoscopy is a useful tool for diagnosing different hair and scalp diseases by their unique visual features.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

Microneedling is a safe and effective treatment for various skin conditions, often preferred for its fewer side effects and shorter recovery time.

Wool follicles are complex, involving interactions between different cell types and structures.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

The document concludes that proper diagnosis and FDA-approved treatments for different types of hair loss exist, but treatments for severe cases often fail and future improvements may focus on hair follicle stem cells.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

A patient with alopecia areata regrew hair after taking tofacitinib and showed changes in certain blood and skin markers.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Some breast cancer chemotherapy can cause permanent hair loss.

We don't fully understand how sunlight damages different types of hair.