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    Did you mean Receptor Activator of Nuclear Factor Kappa-Β Ligand?
    Glossary Receptor Activator of Nuclear Factor Kappa-Β Ligand

    protein that promotes bone resorption by activating osteoclasts

    Receptor Activator of Nuclear Factor Kappa-Β Ligand (RANKL) is a protein that plays a crucial role in bone metabolism by promoting the formation, function, and survival of osteoclasts, the cells responsible for bone resorption. It is also involved in immune system regulation and has been linked to conditions such as osteoporosis and rheumatoid arthritis.

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    1. <i>Ishige sinicola</i> extract stimulates osteoblast proliferation and differentiation via the bone morphogenetic protein 2/runt-related gene 2 signalling pathway Zeitschrift für Naturforschung C · 2019 · 4 citations
    2. RANKL Induces Organized Lymph Node Growth by Stromal Cell Proliferation 2011 · 42 citations
    3. Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately Stem Cell Research & Therapy · 2015 · 113 citations
    4. 17β-estradiol Inhibits the Production of RANTES in Human Keratinocytes Journal of Investigative Dermatology · 2003 · 56 citations
    5. Treatment of Cultured Sebocytes with an EGFR Inhibitor Does Not Lead to Significant Upregulation of Inflammatory Biomarkers Annals of Dermatology · 2011 · 3 citations
    6. TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia Cell Death and Disease · 2016 · 38 citations
    7. Transcriptome Dynamics Reveal Stage-Specific and Melatonin-Triggered Gene Expression Patterns During The Cashmere Growth Cycle in Capra Hircus Research Square (Research Square) · 2021
    8. The role of B cell-activating factor system in autoimmune diseases: mechanisms, disease implications, and therapeutic advances Frontiers in Immunology · 2025 · 4 citations
    9. Nucleic acid-induced chemokine expression in keratinocytes: Implications for skin inflammation Repository of the Academy's Library (Library of the Hungarian Academy of Sciences) · 2025
    10. Identification of potential key genes and pathways associated with the Pashmina fiber initiation using RNA-Seq and integrated bioinformatics analysis Scientific Reports · 2021 · 36 citations
    11. Androgens and androgen receptor action in skin and hair follicles Molecular and Cellular Endocrinology · 2017 · 100 citations
    12. Melatonin Promotes the Development of Secondary Hair Follicles in Adult Cashmere Goats by Activating the Keap1-Nrf2 Signaling Pathway and Inhibiting the Inflammatory Transcription Factors NFκB and AP-1 International Journal of Molecular Sciences · 2023 · 1 citations
    13. Regulation of Semaphorin3A in the process of cutaneous wound healing Cell Death and Differentiation · 2022 · 13 citations
    14. Epidermal Notch1 recruits RORγ+ group 3 innate lymphoid cells to orchestrate normal skin repair Nature Communications · 2016 · 86 citations
    15. Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations Frontiers in immunology · 2022 · 21 citations
    16. Plakophilin 1 suppresses keratinocyte innate immune responses through DExD/H helicases 2026
    17. Suppression of Cutibacterium acnes-Mediated Inflammatory Reactions by Fibroblast Growth Factor 21 in Skin International Journal of Molecular Sciences · 2022 · 7 citations
    18. Nucleic acid-induced chemokine expression in keratinocytes: Implications for skin inflammation PLoS ONE · 2025
    19. Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration Cell Reports · 2023 · 44 citations
    20. Radiofrequency Currents Modulate Inflammatory Processes in Keratinocytes International Journal of Molecular Sciences · 2024 · 3 citations
    21. Peroxisome Proliferator Activated Receptors Gamma Serum levels and Gene Polymorphism in Frontal Fibrosing Alopecia: A Case Control Study Research Square (Research Square) · 2022
    22. YAP/TAZ Signalling Controls Epidermal Keratinocyte Fate International Journal of Molecular Sciences · 2024 · 14 citations
    23. What’s Sex Got to Do With COVID-19? Gender-Based Differences in the Host Immune Response to Coronaviruses Frontiers in Immunology · 2020 · 125 citations
    24. Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis Cell death and differentiation · 2011 · 76 citations
    25. Studying the genetic predisposing factors in the pathogenesis of acne vulgaris Human Immunology · 2011 · 39 citations
    26. Epidermal expression of receptor for advanced glycation end products (RAGE) is related to inflammation and apoptosis in human skin Experimental Dermatology · 2015 · 10 citations
    27. Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice Scientific Reports · 2017 · 113 citations
    28. SPT6 maintains epidermal homeostasis by inhibiting an NF-κB-positive feedback loop to prevent excessive inflammation Cellular and Molecular Immunology · 2026
    29. Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men Cell Stem Cell · 2020 · 139 citations
    30. All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration Stem cell biology and regenerative medicine · 2018