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GlossaryMetabotropic Receptor

A metabotropic receptor is a type of cell surface receptor that, when activated by a neurotransmitter, initiates a cascade of intracellular events through a signaling molecule called a G-protein. Unlike ionotropic receptors, which form ion channels, metabotropic receptors work indirectly to modulate cellular activity, often resulting in longer-lasting and more diverse effects.

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research GABAA Receptor Modulation by Neurosteroids in Models of Temporal Lobe Epilepsies

40 citations, December 2012 in “Epilepsia”

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

research Sebaceous Immunobiology: Skin Homeostasis, Innate Immunity Coordination, Inflammatory Response, and Disease Associations

21 citations, November 2022 in “Frontiers in immunology”

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

research Gamma-Aminobutyric Acid Promotes the Inhibition of Hair Growth Induced by Chronic Restraint Stress

1 citations, March 2023 in “Life sciences”

GABA contributes to stress-related hair loss, and ginkgolide A may help treat it.

research Combined Drug Triads for Synergistic Neuroprotection in Retinal Degeneration

6 citations, May 2022 in “Biomedicine & pharmacotherapy”

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

Atypical Hippocampal Glutamate Receptor Coupled to Phospholipase D Controlling Stretch-Sensitivity in Primary Mechanosensory Nerve Endings Is Homomeric Purely Metabotropic GluK2

research Atypical Hippocampal Glutamate Receptor Coupled to Phospholipase D Controlling Stretch-Sensitivity in Primary Mechanosensory Nerve Endings Is Homomeric Purely Metabotropic GluK2

6 citations, September 2023 in “Experimental physiology”

A special receptor in sensory nerve endings helps control how they respond to stretching.

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