1 citations
,
December 2014 in “Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology” This study reports that a 15-year-old with trichotillomania showed improvement with aripiprazole treatment, though no consensus on treatment exists in the literature.
April 2026 in “Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy” 
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that inhibiting mTORC1 activity with rapamycin significantly increased melanin production and extended hair growth phase in human hair follicles, suggesting potential for managing hair growth and pigmentation disorders.
January 2025 in “International Journal of Trichology” This report describes a rare case of loose anagen hair syndrome in a young Indian child, highlighting its clinical and trichoscopic features.
January 2026 in “Health Science Reports” This study highlights a complex link between hair care and HFRBDs and suggests that personalized hair care strategies could improve condition management and be integrated into professional guidance by clinicians and hair experts.
In this literature review, researchers highlighted that trichotillomania involves dysregulated reward circuits, abnormal sensory processing, and potential genetic factors, advancing both therapeutic strategies and understanding of the condition, but stigma and provider training gaps persist in effective care provision.
April 2024 in “Jurnal Agroindustri Halal/Jurnal agroindustri halal” This study investigated formulations of hair tonic using Hormophysa triquetra seaweed and candlenut extract, finding that the variant with the highest seaweed extract content demonstrated superior physical stability and rapid hair growth in test animals due to its antioxidant properties.
April 2016 in “Journal of the American Academy of Dermatology” A 4-year-old girl had a rare hair disorder affecting only part of her scalp.
December 2023 in “University of Southern Denmark Research Portal (University of Southern Denmark)” This case report discusses a 9-year-old boy diagnosed with uncombable hair syndrome, a rare hair shaft anomaly characterized by blond, frizzy, and unruly hair. The diagnosis was prompted by the boy's mother, who suspected the condition after reading a medical paper on hair shaft anomalies. Molecular genetics confirmed the diagnosis. The report highlights the role of digital access in raising awareness of rare conditions among patients and their families.
April 2016 in “Apollo (University of Cambridge)” This article reviews treatment approaches for trichotillomania, emphasizing differences from OCD therapies and recommending specific management strategies, without providing new experimental findings.
10 citations
,
January 1925 in “Archives of Dermatology” This article discusses a historical case of a rare skin disorder involving alopecia and follicular plugs reported in 1907; it presents no new findings.
20 citations
,
July 1990 in “Pediatrics in Review” This piece explains that 90% to 95% of pediatric alopecia cases are due to four main causes: alopecia areata, telogen effluvium, tinea capitis, and trichotillomania, with diagnosis typically confirmed through careful examination.
2 citations
,
January 1987 in “PubMed” This study reported three related cases of woolly hair syndrome transmitted as a dominant autosomal trait, characterized by fine, frizzy hair and general hair thinning.
August 2026 in “Medicina Clínica Práctica” In this case report, a patient with progressive hair loss linked to hair-pulling during emotional stress showed marked improvement in hair density after treatment with oral N-acetylcysteine and topical minoxidil, along with cessation of the hair-pulling behavior.
November 2019 in “Harper's Textbook of Pediatric Dermatology” This review discusses potential causes of alopecia and hair overgrowth in pediatric patients, detailing diagnostic techniques and treatments, but presents no new research findings.
June 2023 in “Zenodo (CERN European Organization for Nuclear Research)” 
2 citations
,
January 1908 in “Journal of the American Medical Association” Fear of hair-related issues causes significant mental distress, especially in high-stress women.
July 2023 in “Portuguese journal of dermatology and venereology” This study describes a rare case of a 9-year-old boy with simultaneous alopecia areata and trichotillomania, diagnosed through clinical history and trichoscopy, highlighting the complexity of pediatric hair loss caused by psychological and immune factors.
2 citations
,
August 1994 in “Archives of dermatology” This article reports a case of a 19-month-old boy with scalp erythematous papules and hair loss, showing no improvement with initial treatment.
3 citations
,
January 2002 in “Actas Dermo-Sifiliográficas” In this case report, a 23-year-old woman developed localized trichorrhexis nodosa after compulsively applying 3% minoxidil to her scalp for two months.
January 2026 in “Journal of Dermatology & Dermatologic Surgery” In this case report, a 26-year-old man with alopecia universalis, resistant to multiple standard treatments, achieved complete and sustained hair regrowth with ruxolitinib, highlighting its potential as a promising option for patients with refractory AU.
January 2025 in “Digital Repository (National Repository of Grey Literature)” In this study, analysis of questionnaire data from over 111,000 respondents revealed that red hair is significantly associated with a higher level of mental health problems in both men and women, while red-haired women also exhibited poorer overall physical health.
November 2023 in “Scholars academic journal of biosciences” This study highlights a case of trichotillomania with trichophagia in a 7-year-old girl, illustrating the medical complications and need for awareness and collaborative management of this condition, often misdiagnosed due to stigma.
5 citations
,
May 2015 in “JRSM open” If a child is losing a lot of eyelashes and it keeps happening, doctors should look carefully at their health history because it might be a sign of a different health problem.
6 citations
,
September 2024 in “Frontiers in Physiology” This study found that overexpression of R-spondin 3 in a mice model impaired hair morphogenesis and regeneration by reducing hair matrix progenitor cell proliferation, thus disrupting the Wnt pathway's regulation of stem cells.
4 citations
,
April 2018 in “The journal of pediatrics/The Journal of pediatrics” This case report discusses a 6-year-old girl with loose anagen hair syndrome, characterized by painlessly shedding hair, and notes no evidence of benefit from biotin supplementation.
November 2022 in “Journal of Investigative Dermatology” In this study, rapamycin was found to increase hair follicle pigmentation and prolong anagen duration in cultured human scalp hair follicles, suggesting it could be explored as an anti-greying agent.
January 2015 in “Turkiye Klinikleri Journal of Dermatology” This case report highlights a 34-year-old woman with traction alopecia, where diagnosis was clarified by the presence of peripilar keratin sheaths, a useful dermoscopic clue.
4 citations
,
January 1991 in “Dermatology” This article reviews literature on hair casts, shedding light on this rarely discussed hair disorder, along with a case report of a 5-year-old mistakenly treated for head lice.