November 2003 in “Journal of Neurochemistry” This study suggests that the neurosteroid allopregnanolone may play a crucial role in how ethanol affects neurons related to alcohol addiction vulnerability.
11 citations
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January 2016 in “Molecular and Cellular Neuroscience” This study found that thalamic GABAA receptor α4 subunit levels increased after prolonged ethanol exposure and were regulated by phosphorylation and neuroactive steroids following acute high-dose ethanol administration.
February 2026 in “Aesthetic Cosmetology and Medicine” In this case study, a 38-year-old woman with female androgenetic alopecia experienced increased hair density and improved hair structure following ten microneedle mesotherapy sessions combined with saw palmetto supplementation, without adverse effects.
33 citations
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June 1995 in “International journal of legal medicine” This study observed that prolonged water or soil exposure can lead to significant reductions in drug levels in bleached and natural hair samples.
April 2008 in “Annals of General Psychiatry” This study found that social isolation in rats enhanced the effects of ethanol on certain brain steroids, increased GABAA receptor subunits, and amplified ethanol's inhibitory effects on seizures.
January 2024 in “Wiadomości Lekarskie” This presentation explored recent developments in treating alcohol, opioid, and cannabis addiction, highlighting promising pharmacological and behavioral therapies, such as extended-release naltrexone for alcohol use and long-acting buprenorphine for opioids, alongside emerging strategies for cannabis use disorder.
5 citations
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June 2012 in “QJM: An International Journal of Medicine” This article reviews the historical development of pharmacology up to the mid-20th century and outlines its transition from a support role in therapeutics to a distinct scientific discipline, but reports no new findings.
63 citations
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September 2021 in “Journal of Fungi” In this review, the authors highlighted the broad range of therapeutic and health benefits of mushrooms, including antiviral, antibacterial, anticancer, and other protective effects, due to their complex chemical components like polysaccharides and glucans.
January 2023 in “IntechOpen eBooks” This chapter reviews various synthetic methods for creating pharmacologically active diazines, particularly focusing on pyrimidines, and discusses their potential in clinical applications. It also examines novel synthetic strategies that improve the drug-like qualities and safety profiles of these compounds.
4 citations
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October 2017 in “Journal of Mind and Medical Sciences” This overview discusses the mind-body problem and suggests that the brain may be intrinsically part of the mind, processing abstract data without direct interaction, but reports no new research results.
18 citations
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March 2020 in “Frontiers in Neuroendocrinology” This study suggests that synthetic steroid analogues or 5α-reductase modulation could be potential therapeutic strategies for nervous system disorders, but further research on their effects is necessary.
1 citations
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July 2023 in “International Journal of Molecular Sciences” In this study, the researchers reviewed psychiatric drugs approved between 2002 and 2022 to analyze trends in drug repurposing, finding an increased application of repurposing methods, especially through fixed-dose combinations, and highlighting technologies like SmartCube® to predict efficacy from animal models.
7 citations
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May 2017 in “Behavioural brain research” This study found that manipulating neuroactive steroids during early development stages in male rats influences alcohol-induced locomotor sensitivity, suggesting their role in addiction vulnerability.
15 citations
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March 2023 in “Heliyon” This study found that water-soluble beehive extract exhibited anxiolytic, antidepressant, and anti-inflammatory effects in animal models.
36 citations
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April 2019 in “Journal of Herbal Medicine” This review discusses the therapeutic potential of Ganoderma lucidum's secondary metabolites, noting their diverse health benefits, such as anticancer and antioxidant effects, without presenting new experimental results.
January 2024 in “Pharmacokinetics and Pharmacodynamics” This review discusses peptide "biogenic stimulants" from human placenta extracts, highlighting their potential wide-ranging clinical applications across multiple diseases, and reports no new clinical results.
3 citations
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December 1962 in “Australasian Journal of Dermatology” The current state and future directions of the field that studies the connection between the mind and skin are discussed.
January 2009 in “Side effects of drugs annual” This study observed no teratogenic effects of oral decongestants and surprisingly favorable neonatal outcomes in Swedish women who used them during pregnancy.
14 citations
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September 2017 in “Hormones and behavior” This study found that the estrous cycle influences the effect of the δ-GABAAR agonist THIP in reducing binge drinking behavior in female mice, with receptor expression elevated during diestrus.
7 citations
,
January 2019 in “Journal of Analytical Toxicology” This study found that hair samples from chronic tramadol and cannabis users showed positive drug presence for 3-4 months and 6-7 months, respectively, after discontinuation.
2 citations
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January 2000 in “Elsevier eBooks” 38 citations
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January 2012 in “Annales de Toxicologie Analytique” This study found that among bodybuilder-intended drugs from the black market, 33.8% of labeled products and 52.5% of steroidal oily solutions contained ingredients not matching their labels.
16 citations
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October 2018 in “BMC Complementary and Alternative Medicine” In this animal study, the methanolic extract of Crataeva nurvala leaves was found to possess sedative and anxiolytic properties, potentially linked to GABAergic activity and certain neuroactive compounds.
August 2008 in “European Neuropsychopharmacology” RY-023, a specific drug, can improve early stage memory learning without affecting general activity in rats, but it's less effective for later learning stages and doesn't impact memory recall.
63 citations
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August 1996 in “Forensic Science International” In this study, bleaching and perming were found to significantly reduce opiate concentrations in both spiked and naturally opiate-positive human hair samples.
35 citations
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November 2019 in “Frontiers in Neuroendocrinology” This review discusses the sex differences in neuroactive steroid synthesis and their implications for nervous system functions and potential therapeutic approaches, but it provides no new experimental results.
This abstract details known indications, categories, and potential reactions for various drugs, including anorexiants, estrogens, NSAID analgesics, cardiac glycosides, and migraine preventives, without reporting new clinical results.
4 citations
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January 2018 in “General Physiology and Biophysics” In this study, finasteride-treated WAG/Rij rats showed a significant increase in spike-wave discharges when administered endogenous steroids THPROG and THDOC, indicating potential exacerbation of absence seizures.
6 citations
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July 2018 in “Scientific Reports” In this study, gene expression changes in rat whisker follicles after methamphetamine administration may serve as indicators of the drug's rewarding effects and potential addiction pathways.
This study provides detailed taxonomic and pharmacognostic analyses to authenticate and standardize seven herbal medicines, aiding in their differentiation from common adulterants for improved identification and classification.