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S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Many people with alopecia experience high levels of social anxiety, anxiety, and depression, and while wigs can boost confidence, they may also cause anxiety.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Doctors need to be better prepared to assess and treat obesity in patients.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Some systemic treatments work for nail psoriasis but can have serious side effects.

Women with excess body hair feel psychological distress influenced by societal beauty standards, but distress isn't directly linked to the amount of hair.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Alopecia significantly lowers women's quality of life, with psychological and social challenges, highlighting the importance of early treatment and support.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

The research found that anovulatory young women have higher androgen and hormone levels than those who ovulate, suggesting immature hormonal regulation rather than a specific condition.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Despite progress in treatment, the exact cause of Alopecia areata is still unknown.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

The document concludes that understanding and treating hair loss requires recognizing its various types and using appropriate diagnostic tools and treatments.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

People with hair loss conditions experience more anxiety, depression, and a lower quality of life than those without these conditions.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

People with androgenetic alopecia have more personality disorders and mental health symptoms; treatment may help.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.

The article suggests using four questions to tell apart necessary medicalization from excessive medicalization, focusing on problem significance, social expectations, medical understanding, and effective resolution.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Early and personalized treatment for hair loss in young people is crucial to prevent permanent damage and should include psychological support.