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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Intermediate hair follicles are a better model for studying hair growth and testing hair loss treatments.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.

Caucasian and Asian women with PCOS generally show similar symptoms, except Asian women have less chest hair.

The document concludes that lifestyle changes and medical treatments can significantly reduce symptoms of Hidradenitis Suppurativa, a chronic skin condition.

Niacin derivatives may increase hair fullness in women with hair loss.

Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Modified keratin binds better to hair, especially bleached hair.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Follicular Unit Transplantation is an effective and safe treatment for hair loss due to scarring.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

Chronic scalp pain in trichodynia involves both body-wide and localized increased pain sensitivity.

Biologic treatments for Crohn's disease and ulcerative colitis can cause skin problems, and doctors should adjust treatment if these occur.

Melanoma development can be linked to the breakdown of skin's melanin-producing units.

Cyclosporine combined with corticosteroids is more effective for severe alopecia areata than cyclosporine alone.

The anti-ageing treatment market is growing by exploiting fears of ageing with unproven promises, which could harm public trust and genuine science.

X-ray microbeams can mimic cosmic rays' effects on tissue, aiding wound healing and hair growth.

Glutamic acid helps increase hair growth in mice.

Isotretinoin is effective for treating dissecting cellulitis, but recurrence is common.

Older adults still engage in sexual activities but face challenges like health issues and lack of professional support, highlighting the need for better healthcare provider education and research on sexual fulfillment in old age.

No definitive link between finasteride and male breast cancer, but further research is needed.