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    Did you mean Pro-inflammatory cytokines?
    Glossary Pro-inflammatory cytokines

    signaling molecules that trigger inflammation in the body

    Pro-inflammatory cytokines are signaling molecules released by immune cells that promote inflammation in the body. They play a crucial role in the immune response by helping to fight off infections and heal injuries, but excessive or chronic production can lead to inflammatory diseases such as rheumatoid arthritis, psoriasis, and alopecia areata. Examples include tumor necrosis factor-alpha (TNF-α), interleukin-1 (IL-1), and interleukin-6 (IL-6).

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    1. Proinflammatory cytokines regulate epidermal stem cells in wound epithelialization Stem Cell Research & Therapy · 2020 · 65 citations
    2. FC053 Pro-inflammatory cytokine cascade in human plucked hair 1997
    3. Advanced glycation end-products inhibit mesenchymal-epidermal interaction by up-regulating proinflammatory cytokines in hair follicles European Journal of Dermatology · 2015 · 3 citations
    4. The effects of methylated flavonoids on depression-like activity and pro-inflammatory cytokine thresholds in mice induced by repeated finasteride administration European Journal of Inflammation · 2021 · 1 citations
    5. A new TH17 cytokine in hidradenitis suppurativa: antimicrobial and pro-inflammatory role of IL-26 2020
    6. Treatment with Light-Emitting Diodes of Wavelength 863 nm Delays DMBA/TPA-Induced Skin Tumor Formation and Decreases Proinflammatory Cytokine Levels in ICR Mice BioMed Research International · 2022 · 2 citations
    7. Epidermal keratinocytes initiate wound healing and pro-inflammatory immune responses following percutaneous schistosome infection 2015 · 39 citations
    8. Healthy individuals genetically at-risk for the development of Pemphigus vulgaris or Alopecia areata share disease-like cytokine dysregulation Frontiers in Immunology · 2025 · 1 citations
    9. Possible Immunomodulating Effect of Retinol on Cytokines Secretion in Patients with Recurrent Furunculosis Archivum Immunologiae et Therapiae Experimentalis · 2017 · 4 citations
    10. Hollow polydopamine nanoparticles loading with peptide RL-QN15: a new pro-regenerative therapeutic agent for skin wounds Journal of Nanobiotechnology · 2021 · 47 citations
    11. From Primary MSC Culture of Adipose Tissue to Immortalized Cell Line Producing Cytokines for Potential Use in Regenerative Medicine Therapy or Immunotherapy International Journal of Molecular Sciences · 2021 · 13 citations
    12. Androgen receptor–mediated inhibition of cutaneous wound healing 2002 · 108 citations
    13. Altered skin development and impaired proliferative and inflammatory responses in transgenic mice overexpressing the glucocorticoid receptor The FASEB Journal · 2001 · 92 citations
    14. Keratin 17 in disease pathogenesis: from cancer to dermatoses Journal of pathology · 2018 · 62 citations
    15. Influence of substance-P on cultured sebocytes Archives of Dermatological Research · 2008 · 46 citations
    16. Bioengineering a humanized acne microenvironment model: Proteomics analysis of host responses to <i>Propionibacterium acnes</i> infection <i>in vivo</i> PROTEOMICS · 2008 · 40 citations
    17. A dopamine-methacrylated hyaluronic acid hydrogel as an effective carrier for stem cells in skin regeneration therapy Cell Death and Disease · 2022 · 39 citations
    18. An Animal Model of Trichloroethylene-Induced Skin Sensitization in BALB/c Mice International journal of toxicology · 2015 · 36 citations
    19. Chronic prostatitis and chronic pelvic pain in men: aetiology, diagnosis and management<sup>1</sup> Journal of the European Academy of Dermatology and Venereology · 2002 · 35 citations
    20. Stress and Psychoneuroimmunologic Factors in Dermatology Dermatologic Clinics · 2005 · 34 citations
    21. Extracellular vesicles from IFN-γ-primed mesenchymal stem cells repress atopic dermatitis in mice Journal of Nanobiotechnology · 2022 · 29 citations
    22. Activation of TRPV3 Inhibits Lipogenesis and Stimulates Production of Inflammatory Mediators in Human Sebocytes—A Putative Contributor to Dry Skin Dermatoses Journal of Investigative Dermatology · 2018 · 26 citations
    23. Research gaps in medical treatment of transgender/nonbinary people Journal of Clinical Investigation · 2021 · 19 citations
    24. Pathogenetic Characteristics of Mesenchymal Stem Cells in Hidradenitis Suppurativa JAMA dermatology · 2018 · 19 citations
    25. Epidermolysis Bullosa Simplex Caused by Distal Truncation of BPAG1-e: An Intermediate Generalized Phenotype with Prurigo Papules Journal of Investigative Dermatology · 2017 · 14 citations
    26. Cutaneous manifestations associated with immune checkpoint inhibitors Frontiers in immunology · 2023 · 14 citations
    27. Janus Kinase Inhibitors in Dermatology: Part 1 — General Considerations and Applications in Vitiligo and Alopecia Areata Actas Dermo-Sifiliográficas · 2021 · 14 citations
    28. Increased Macrophage Migration Inhibitory Factor (MIF) in the Sera of Patients with Extensive Alopecia Areata 2002 · 14 citations
    29. Pectin Nanoparticle-Loaded Soft Coral Nephthea sp. Extract as In Situ Gel Enhances Chronic Wound Healing: In Vitro, In Vivo, and In Silico Studies Pharmaceuticals · 2023 · 10 citations
    30. Nuclear factor (erythroid-derived 2)-like-2 pathway modulates substance P–induced human mast cell activation and degranulation in the hair follicle The Journal of Allergy and Clinical Immunology · 2018 · 8 citations