101 citations,
April 1994 in “Baillière's clinical endocrinology and metabolism” 5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
52 citations,
October 2012 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
25 citations,
March 2000 in “Journal of Endocrinological Investigation” Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
99 citations,
June 2005 in “Journal of Cosmetic Dermatology” Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.
90 citations,
October 1998 in “Animal Reproduction Science” Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.
69 citations,
November 2010 in “Middle East Fertility Society Journal” PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.
47 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Premature graying of hair may suggest health issues and currently lacks effective treatments.
11 citations,
June 2022 in “Frontiers in immunology” New protein changes may be involved in the immune attack on hair follicles in alopecia areata.
11 citations,
December 1987 in “Aesthetic Plastic Surgery” The document concludes that the hCG protocol may help in obesity treatment and could be scientifically justified, but more research is needed.
3 citations,
October 2007 in “Expert Review of Dermatology” Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.
August 2018 in “Journal of the American Academy of Dermatology” Reflectance confocal microscopy helped diagnose and manage a woman's hair loss without needing a biopsy.
8 citations,
December 2022 in “International journal of molecular sciences” Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
38 citations,
January 2017 in “PPAR Research” PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.
1 citations,
August 2005 in “Springer eBooks” Alopecia areata is an autoimmune disease with genetic links, treatable with certain medications, and can affect mental health.
16 citations,
January 2022 in “International journal of molecular sciences” Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.
2 citations,
April 2023 in “Pharmaceuticals” Scopolin and scopoletin from Merremia peltata leaves may help treat hair loss and showed promising results in rabbit tests.
March 2024 in “EMBO molecular medicine” Antiviral drugs, especially daclatasvir, may be a new treatment for a rare skin disease, improving survival and reducing symptoms in mice.
December 2023 in “Clinical, cosmetic and investigational dermatology” The new method combining dermoscopy and Reflectance Confocal Microscopy is more effective for evaluating vitiligo.
1 citations,
August 2023 in “Advanced Drug Delivery Reviews” Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.
June 2023 in “Frontiers in Genetics” Genes related to calcium signaling and lipid metabolism are important for curly hair in Mangalitza pigs.
19 citations,
October 2016 in “Journal of oncology pharmacy practice” A cancer patient's hair became permanently curly after treatment with nivolumab.
164 citations,
September 2010 in “PLANT PHYSIOLOGY” Nitric oxide helps Solanum nigrum adapt to long-term zinc toxicity by changing root growth and metal balance.
July 2024 in “Research Square (Research Square)” Certain proteins can either protect against or increase the risk of hypertrophic scars.
February 1994 in “Archives of Dermatology” Both parties agree that cell death is important in the hair cycle, but they have different views on the role of the catagen phase and hair shedding.
April 2023 in “Journal of Investigative Dermatology” Using DNase enzymes to break down harmful NETs could be a new treatment for Stevens-Johnson syndrome and toxic epidermal necrolysis.
8 citations,
February 1994 in “Archives of Dermatology” Basaloid follicular hamartoma's appearance can be similar to other skin conditions, and diagnosis should consider both the look and behavior of the tumor.
28 citations,
March 2009 in “Clinical and Experimental Dermatology” There is no significant link between male pattern baldness and insulin resistance.
2 citations,
February 1994 in “Archives of Dermatology” The debate focuses on the role of catagen and hair shedding mechanisms in telogen effluvium.
8 citations,
January 2018 in “European journal of dermatology/EJD. European journal of dermatology” The girl's regrown brown hair had less of certain pigments than her original black hair.
1 citations,
July 2016 in “Prescriber” Minoxidil and spironolactone slow hair loss in women.