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    Glossary Pro-inflammatory markers

    substances indicating inflammation in the body

    Pro-inflammatory markers are substances in the body that indicate the presence of inflammation. These markers, such as cytokines and C-reactive protein (CRP), are produced by the immune system and can be measured in blood tests to help diagnose and monitor conditions like infections, autoimmune diseases, and even hair loss disorders like alopecia.

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    1. Epidermal keratinocytes initiate wound healing and pro-inflammatory immune responses following percutaneous schistosome infection 2015 · 39 citations
    2. Mesenchymal Stem Cells Antagonize IFN-Induced Proinflammatory Changes and Growth Inhibition Effects via Wnt/β-Catenin and JAK/STAT Pathway in Human Outer Root Sheath Cells and Hair Follicles International journal of molecular sciences · 2021 · 14 citations
    3. 415 Targeting inflammation and specialized pro-resolving mediators to reinforce barrier function and scalp homeostasis. Journal of Investigative Dermatology · 2022
    4. The effects of methylated flavonoids on depression-like activity and pro-inflammatory cytokine thresholds in mice induced by repeated finasteride administration European Journal of Inflammation · 2021 · 1 citations
    5. Comparative Evaluation of Biomarkers of Inflammation Among Indian Women With Polycystic Ovary Syndrome (PCOS) Consuming Vegetarian vs. Non-vegetarian Diet Frontiers in Endocrinology · 2019 · 28 citations
    6. Erlotinib-Induced Skin Inflammation Is IL-1 Mediated in KC-Tie2 Mice and Human Skin Organ Culture 2014 · 15 citations
    7. Dermal‐Epidermal Cross‐Talk: Differential Interactions With Microvascular Endothelial Cells Journal of Cellular Physiology · 2016 · 6 citations
    8. Single dose gamma irradiation induced angiogenesis in rat skin hair follicles Internatuinal Journal of Radiation Research · 2020 · 3 citations
    9. 0975 Single-cell transcriptomic profiling reveals distinct immunopathogenic programs in alopecia totalis/universalis compared to patchy alopecia areata Journal of Investigative Dermatology · 2026
    10. Microarray Gene Expression Analysis of Lesional Skin in Canine Pemphigus Foliaceus Veterinary sciences · 2024
    11. Human Hair Follicle-Derived Mesenchymal Stromal Cells from the Lower Dermal Sheath as a Competitive Alternative for Immunomodulation Biomedicines · 2022 · 7 citations
    12. The immunopathobiology of lichen planopilaris [Thesis]. Manchester, UK: The University of Manchester; 2011. · 2011 · 2 citations
    13. The senescence-like activity of BMS-470539 is associated with anti-fibrotic actions in models of dermal fibrosis Arthritis Research & Therapy · 2025
    14. 711 Small molecule wnt pathway inhibitor (SM04755) as a potential topical psoriasis treatment Journal of Investigative Dermatology · 2017
    15. Evaluation of the Treatment Effect of <i>Aloe vera</i> Fermentation in Burn Injury Healing Using a Rat Model Mediators of inflammation · 2019 · 15 citations
    16. Proinflammatory Event of Ozonized Olive Oil in Mice Ozone Science and Engineering · 2009 · 13 citations
    17. SARS-CoV-2 Spike Protein S1-Mediated Endothelial Injury and Pro-Inflammatory State Is Amplified by Dihydrotestosterone and Prevented by Mineralocorticoid Antagonism Viruses · 2021 · 50 citations
    18. Efficacy and Potential Mechanisms of Naringin in Atopic Dermatitis International Journal of Molecular Sciences · 2024 · 4 citations
    19. Therapeutic effect of finasteride through its antiandrogenic and antioxidant role in a propionic acid-induced autism model: Demonstrated by behavioral tests, histological findings and MR spectroscopy Neuroscience Letters · 2022 · 3 citations
    20. Potential Treatment of Steroid‐Resistant Alopecia Areata Using Allogeneic Exosomes Derived From Adipose Tissue Mesenchymal Stromal Cells: A Case Report Clinical Case Reports · 2026
    21. Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells Cells · 2019 · 51 citations
    22. O05 Distinct epidermal cell populations and single-cell gene expression signatures are associated with <i>Staphylococcus aureus</i> in atopic dermatitis British Journal of Dermatology · 2026
    23. Extracellular vesicles from IFN-γ-primed mesenchymal stem cells repress atopic dermatitis in mice Journal of Nanobiotechnology · 2022 · 29 citations
    24. Role of Cytotoxic T Cells in Chronic Alopecia Areata Journal of Investigative Dermatology · 2000 · 127 citations
    25. Development of Autoimmune Hair Loss Disease Alopecia Areata Is Associated with Cardiac Dysfunction in C3H/HeJ Mice PLOS ONE · 2013 · 18 citations
    26. Influence of substance-P on cultured sebocytes Archives of Dermatological Research · 2008 · 46 citations
    27. Nuclear factor (erythroid-derived 2)-like-2 pathway modulates substance P–induced human mast cell activation and degranulation in the hair follicle The Journal of Allergy and Clinical Immunology · 2018 · 8 citations
    28. Systemic Circulating Leptin – Aiding New Dimension of Immune-Related Skin Carcinogenesis and Lipid Metabolism South East European Journal of Immunology · 2023 · 2 citations
    29. Neuroprotective and immunomodulatory effects of human hair follicle stem cells on streptozotocin-induced memory impairment in rats: insights into inflammation and neurotrophic mechanisms 2025
    30. Indications for Peripheral and Central Sensitization in Patients With Chronic Scalp Pain (Trichodynia) The Clinical Journal of Pain · 2012 · 16 citations