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Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

New steroids were effective in blocking male hormone receptors in hamster prostates.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.

Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

New sulfur-containing steroid analogs show promise for more targeted medical treatments.

A natural steroid in the body may protect against eye damage in glaucoma.

Neurosteroids show promise for treating epilepsy and more research is needed.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Finasteride slows down motherly behavior in first-time pregnant rats.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Progesterone boosts alcohol's effect on brain, finasteride counters it.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride blocks progesterone's effect on absence seizures in rats.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.