research Androgen Excess in Women: Experience with Over 1000 Consecutive Patients
Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.
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research Use of Chemotherapy During Human Pregnancy
Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.
research Multiple Sclerosis: Side Effects of Interferon Beta Therapy and Their Management
The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.
research Skin Wound Healing in Humans and Mice: Challenges in Translational Research
The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth
Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.
research Chronic Telogen Effluvium: Increased Scalp Hair Shedding in Middle-Aged Women
Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.
research A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss
5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.
research Medical Treatments for Male and Female Pattern Hair Loss
Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.
research Dermatoses of Pregnancy
Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.
research Skin Aging and Menopause: Implications for Treatment
Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.
research Safety of Dermatologic Medications in Pregnancy and Lactation
Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.
research Estrogens and Aging Skin
Estrogen therapy can reduce skin aging but has cancer risks.
research Drug-Induced Hair Loss and Hair Growth
Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.
research The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling
Cathepsin L is essential for normal hair growth and development.
research Lupus Erythematosus: Systemic and Cutaneous Manifestations
Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
research Effects of Flutamide and Finasteride on Rat Testicular Descent
Androgens, like testosterone, are crucial for early testicular descent in rats.
research Hormone Replacement Therapy and the Skin
Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.
research The Distribution of Estrogen Receptor Beta Is Distinct to That of Estrogen Receptor Alpha and the Androgen Receptor in Human Skin and the Pilosebaceous Unit
Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).
research Addressing Continuous Data for Participants Excluded from Trial Analysis: A Guide for Systematic Reviewers
The conclusion is that the risk of losing significance in meta-analysis results increases with smaller effects and more missing data, and using the median standard deviation for imputation is recommended.
research Obesity and the Skin
Obesity is linked to various skin problems and may increase the risk of skin cancer.
research 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder
High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
research Histopathologic Evaluation of Alopecias
The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.
research Dermatoses of Pregnancy: Clues to Diagnosis, Fetal Risk, and Therapy
The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.
research Epidemiology of Vitiligo, Associated Autoimmune Diseases, and Audiological Abnormalities: Ankara Study of 80 Patients in Turkey
Vitiligo is linked to autoimmune diseases and hearing issues, so hearing tests are recommended for patients.
research Role of Cholesterol Sulfate in Epidermal Structure and Function: Lessons from X-Linked Ichthyosis
Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
research Flares of Systemic Lupus Erythematosus During Pregnancy and the Puerperium: Prevention, Diagnosis, and Management
Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.
research Evaluation and Diagnosis of the Hair Loss Patient
To diagnose hair loss, use a systematic approach including history, exams, and tests.
research Diagnosis of Hyperandrogenism: Clinical Criteria
The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.
research Zinc Deficiency and Its Management in the Pediatric Population: A Literature Review and Proposed Etiologic Classification
Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.
research Safety of Dermatologic Medications in Pregnancy and Lactation
Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.