June 2014 in “Toxicologie analytique et clinique/Annales de toxicologie analytique” In this study, researchers found that while chest hair can be a reliable alternative to scalp hair for ethylglucuronide testing, seasonal factors may affect concentration levels and should be considered in result interpretation.
November 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Keratin 79 cells help form and regenerate hair canals.
April 2010 in “Cancer Research” In this study, Stat3 activation in transgenic mice led to a decrease in stem cells in the hair follicle bulge, suggesting its crucial role in epidermal growth and stem cell maintenance.
May 2008 in “Nature Clinical Practice Urology” Finasteride may be cost-effective for preventing prostate cancer in high-risk groups.
February 2023 in “Journal of The American Academy of Dermatology” This study found that transgender and gender diverse patients on masculinizing hormone therapy had 2.5 times the rate of androgenetic alopecia compared to cisgender women.
This study found that androgenetic alopecia in Chinese college students is more prevalent in males and is significantly associated with rosacea, with clinic patients experiencing a higher disease burden.
215 citations
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January 2011 in “Reproductive Biology and Endocrinology” Among reproductive-aged women in Iran, this study found that the prevalence of PCOS varied significantly depending on the diagnostic criteria used, with estimates ranging from 7.1% to 14.6%.
123 citations
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December 1997 in “Calcified Tissue International” This study concluded that higher androgen levels in males and specific skeletal sites may contribute to differences in skeletal morphology, with glucocorticoids, E2, and D3 enhancing androgen receptor expression and mitogenic action in human osteoblastic cells.
89 citations
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August 2008 in “Human genetics” This study found that the EDAR 1540T/C genetic variant is significantly associated with hair thickness variation in Japanese populations, enhancing previously observed associations in Southeast Asian groups.
73 citations
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May 2011 in “Annals of Epidemiology” This study found that childhood use of hair oils and perms was associated with earlier onset of menarche among women of various racial and ethnic backgrounds.
44 citations
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February 2021 in “Scientific Reports” This study found that specific mutations in the spike protein of SARS-CoV-2 may significantly alter its structure and affect how it binds to certain inhibitors, but experimental studies are needed to confirm potential clinical implications.
37 citations
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April 2012 in “British Journal of Dermatology” This study found that among middle-aged Korean women, those with metabolic syndrome had a higher risk of androgenetic alopecia, while no significant association was observed in men.
36 citations
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May 2005 in “BMC dermatology” This study found that topical diphenylcyclopropenone was effective in treating severe alopecia areata but had a high relapse rate and was often accompanied by side effects like eczema and lymphadenopathy.
29 citations
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April 2019 in “BMJ. British medical journal” This study concluded that men with benign prostatic hyperplasia receiving steroid 5α-reductase inhibitors, such as dutasteride or finasteride, have a higher risk of developing new onset type 2 diabetes compared to those taking tamsulosin.
23 citations
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September 2013 in “Molecular Carcinogenesis” This study found that constitutively active Stat3 in transgenic mice led to reduced keratinocyte stem cell populations in hair follicles, altering stem/progenitor cell dynamics and homeostasis.
18 citations
,
September 2016 in “International Journal of Molecular Sciences” This study reports that PDRN, commonly used for wound healing, may also have anti-melanogenesis and potential skin whitening effects in both experimental models and clinical settings.
17 citations
,
August 2015 in “Journal of Animal Science” In this study, researchers found that specific SNPs in the MTR gene are significantly associated with wool production and quality traits in Chinese Merino sheep, suggesting the gene's potential for sheep breeding.
16 citations
,
January 2014 in “International Journal of Trichology” This study found that male Indian patients under 30 with early androgenetic alopecia were more likely to have metabolic syndrome compared to age-matched controls.
14 citations
,
December 2017 in “Journal of Bone and Mineral Metabolism” This study found that women with polycystic ovary syndrome had a higher risk of fractures, including osteoporotic and specific types like spine and forearm fractures, compared to those without the condition.
14 citations
,
February 2017 in “Scientific Reports” Certain variations of the HDAC9 gene can increase or decrease stroke risk in the Chinese population.
13 citations
,
July 2024 in “BMC Genomics” In this study, researchers found that single SNPs have a small genetic effect on phenotypes in Inner Mongolia cashmere goats, and constructing haplotypes from associated SNPs may uncover complex variations in cashmere traits, aiding genomics and breeding efforts.
13 citations
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January 2019 in “Journal of the American Academy of Dermatology” This study found that those with pityriasis rubra pilaris reported worse quality of life than patients with most other dermatologic conditions, impacting daily activities and emphasizing its severe life quality implications.
13 citations
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January 2018 in “International Journal of Dermatology” This clinical study on fibrosing alopecia in a pattern distribution among a Latin American population reports no new results but addresses this specific condition in its demographic context.
12 citations
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September 2011 in “Archives of Dermatological Research” This study found that policemen aged 40-59 years had a twofold higher prevalence of androgenetic alopecia compared to the general population, with obesity and sunlight exposure contributing to the risk.
12 citations
,
April 2022 in “Dermatology and therapy” This study reports that patients with alopecia areata in the US incur significantly higher healthcare utilization and expenses, primarily driven by ambulatory and pharmacy costs, compared to matched controls.
11 citations
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June 2019 in “International journal of gynaecology and obstetrics” This study found that among women with PCOS in Haryana, a larger proportion lived in urban areas, suggesting lifestyle and dietary factors may influence prevalence.
11 citations
,
August 2017 in “Journal of Cosmetic Dermatology” This study reports that a wide variety of patients utilize anti-aging treatments, are largely unfamiliar with their options, and are more likely to pursue treatment if informed by a dermatologist.
11 citations
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December 2013 in “International Journal of Dermatology” This study found that variations in the IL16 gene, specifically SNPs rs17875491 and rs11073001, may be associated with increased risk and phenotype expression of alopecia areata in the Korean population.
10 citations
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November 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reported higher dihydrotestosterone and testosterone levels in balding Korean and Caucasian subjects compared to non-balding controls, with variations suggesting racial differences in androgen metabolism.