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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The Rotterdam Study aims to understand various diseases in older adults.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.

Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

EDA2R gene linked to hair loss.

A new gene, JMJD1C, may affect testosterone levels in men.

Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.

Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.

Mutations in the DSG4 gene can cause a rare hair disorder similar to monilethrix.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.

Finasteride can reduce fertility in some men, but stopping it increases sperm count.

A gene called HDAC9 might be a new factor in male-pattern baldness.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.