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A specific gene variant causes severe skin issues and increases infection risk, requiring careful medical monitoring.

A boy with progeria had eye problems and signs of aging like hair loss and skin wrinkling.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

Natural skincare products may help reduce sun damage and support the skin's daily cycle.

The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Adding a second method to PROTACs could improve cancer treatment.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

FOXC1 boosts SFRP1 in hair loss, suggesting new treatments.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Human hair keratin might be good for filtering out harmful substances from water.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

A male with aromatase deficiency improved bone health with estradiol treatment.

Plantain leaf extract reduces liver oxidative stress in malaria-infected mice.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Male pattern hair loss may have evolved to promote younger fathers for offspring health and survival, encouraging monogamy and paternal nurturing.

Doxazosin mesylate and saw palmetto cause genetic changes in fruit flies.

Different conditions affect how hair proteins assemble, and certain mutations can change their structure.

The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.