Systematic Analysis of Somatic Mutations Driving Cancer: Uncovering Functional Protein Regions in Disease Development

    May 2016 in “ Biology Direct
    Bálint Mészáros, András Zeke, Attila Reményi … Zsuzsanna Dosztányi
    Studysummary This study presents iSiMPRe, a method identifying protein regions enriched in mutations, revealing potential cancer-related genes and enhancing understanding of mutation effects across a wide range of cancer types.
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    Research cited in this study 1

    1. Human TSC2-Null Fibroblast-Like Cells Induce Hair Follicle Neogenesis and Hamartoma Morphogenesis Nature Communications · 2011