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![Intracrinology and the Skin](/images/research/d755c4c2-4751-4c15-bbea-06693092a858/small/15511.jpg)
research Intracrinology and the Skin
DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
![Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth](/images/research/3cd6ce89-2a40-485c-8c45-59fd1ffe3d72/small/13740.jpg)
research Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth
Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
![Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date](/images/research/c47a3f79-d136-49f3-956f-a90699948847/small/4758.jpg)
research Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date
Finasteride shows promise for female hair loss, but more research needed.
![Dutasteride Reduces Alcohol’s Sedative Effects in Men in a Human Laboratory Setting and Reduces Drinking in the Natural Environment](/images/research/7a97cddd-f791-4dd3-93f4-85733d97d1d9/small/20279.jpg)
research Dutasteride Reduces Alcohol’s Sedative Effects in Men in a Human Laboratory Setting and Reduces Drinking in the Natural Environment
Dutasteride makes alcohol less sedating and may lead to less drinking in men.
![Persistent Sexual and Nonsexual Adverse Effects of Finasteride in Younger Men](/images/research/6293cc9c-0c0d-43bb-8f4c-c47f82182fac/small/3384.jpg)
research Persistent Sexual and Nonsexual Adverse Effects of Finasteride in Younger Men
Finasteride can cause sexual problems and depression in young men.
![Dihydrotestosterone Induces p27 Degradation via Direct Binding with SKP2 in Ovarian and Breast Cancer](/images/research/57e0759a-11fc-4c67-a4c8-0ee8dd7756aa/small/36016.jpg)
research Dihydrotestosterone Induces p27 Degradation via Direct Binding with SKP2 in Ovarian and Breast Cancer
Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.
![Hyperandrogenism in Adolescent Girls](/images/research/29ccdec2-1f52-45b1-b06e-8e0863aab64c/small/14636.jpg)
research Hyperandrogenism in Adolescent Girls
The conclusion is that a thorough approach is needed to diagnose and manage hyperandrogenism in teenage girls, recognizing its major psychological and health effects.
![Optimization of Microstructured Biodegradable Finasteride Formulation for Depot Parenteral Application](/images/research/e10f31f4-92ba-4018-b72d-1679f3c4fc0c/small/3760.jpg)
research Optimization of Microstructured Biodegradable Finasteride Formulation for Depot Parenteral Application
Improved finasteride formula allows slow, sustained release and better absorption for patients.
![The Anti-Androgen Combination, Flutamide Plus Finasteride, Paradoxically Suppressed LH and Androgen Concentrations in Pregnant Spotted Hyenas, but Not in Males](/images/research/d44074d4-cf30-44c8-b486-25c1127a3731/small/3033.jpg)
research The Anti-Androgen Combination, Flutamide Plus Finasteride, Paradoxically Suppressed LH and Androgen Concentrations in Pregnant Spotted Hyenas, but Not in Males
Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.
![Adrenal Cortex Tumors and Hyperplasias](/images/research/b0ebf56c-7a7a-4a3f-8b31-017e8e89423b/small/21010.jpg)
research Adrenal Cortex Tumors and Hyperplasias
Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.
![Antiandrogens and Androgen Inhibitors in Dermatologic Treatments](/images/research/925d19de-8ca0-4d51-99ff-222ace6cb768/small/12037.jpg)
research Antiandrogens and Androgen Inhibitors in Dermatologic Treatments
Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
![Acne Protection: Measures and Miseries](/images/research/444f7788-d541-4fa9-b1f4-4757cc0bedf3/small/17783.jpg)
research Acne Protection: Measures and Miseries
Acne can be managed with various treatments and requires psychological support due to its emotional impact.
![Reduction of Diameter of Hair Shaft Among Women With Hirsutism](/images/research/64d42512-2294-4fb0-ac2f-965c77f31fec/small/28071.jpg)
research Reduction of Diameter of Hair Shaft Among Women With Hirsutism
Aldactone effectively reduces hair thickness in women with excessive hair growth, both alone and with other treatments.
![An Update on Congenital Adrenal Hyperplasia](/images/research/8ea69b0b-1349-4a3f-9b8b-e25059c42736/small/15328.jpg)
research An Update on Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.
![Dermatologic Signs in Patients with Eating Disorders](/images/research/fa892e3c-545c-408a-af0e-36023802bfb2/small/25019.jpg)
research Dermatologic Signs in Patients with Eating Disorders
Eating disorders like anorexia and bulimia cause skin problems, and dermatologists can help detect these disorders early for better treatment outcomes.
![Tumor Regression Predicts Higher Risk of Sentinel Node Involvement in Thin Cutaneous Melanomas](/images/research/4e300b8a-58df-48a7-8308-baf37e11953e/small/25077.jpg)
research Tumor Regression Predicts Higher Risk of Sentinel Node Involvement in Thin Cutaneous Melanomas
Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.
![Hair: What Is New in Diagnosis and Management?](/images/research/f720ed6b-c511-4085-8ae8-601678cf8c19/small/3252.jpg)
research Hair: What Is New in Diagnosis and Management?
Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.
![The Safety of 52 Weeks of Oral DHEA Therapy for Postmenopausal Women](/images/research/1627c059-5cf7-4b6c-8f55-2156408c8606/small/14945.jpg)
research The Safety of 52 Weeks of Oral DHEA Therapy for Postmenopausal Women
Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.
![GABAA Receptor Modulation by Neurosteroids in Models of Temporal Lobe Epilepsies](/images/research/5e3d5823-2153-4201-9831-f38524ea1683/small/14673.jpg)
research GABAA Receptor Modulation by Neurosteroids in Models of Temporal Lobe Epilepsies
Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
![Prevalence of Hyperandrogenic States in Late Adolescent and Young Women: Epidemiological Survey on Italian High-School Students](/images/research/981d44c7-ac61-48f8-9104-e7d3ea10f1e5/small/14503.jpg)
research Prevalence of Hyperandrogenic States in Late Adolescent and Young Women: Epidemiological Survey on Italian High-School Students
Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.
![Acne in Women](/images/research/cae19beb-e135-4979-a70e-af421746ad61/small/18647.jpg)
research Acne in Women
Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.
![Androgenetic Alopecia as an Early Marker of Benign Prostatic Hyperplasia](/images/research/87339ffe-8383-49ca-bc98-dad1cff7c659/small/3141.jpg)
research Androgenetic Alopecia as an Early Marker of Benign Prostatic Hyperplasia
Early hair loss may indicate prostate issues.
![Metabolic Syndrome in Greek Women with Polycystic Ovary Syndrome: Prevalence, Characteristics, and Associations with Body Mass Index. A Prospective Controlled Study](/images/research/a24afabf-f2b9-4e70-a380-14160b13d48e/small/18576.jpg)
research Metabolic Syndrome in Greek Women with Polycystic Ovary Syndrome: Prevalence, Characteristics, and Associations with Body Mass Index. A Prospective Controlled Study
Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.
![Effects of Finasteride on Chronic and Acute Ethanol Withdrawal Severity in the WSP and WSR Selected Lines](/images/research/0532966b-b031-454b-a692-51ccbdc9ed99/small/2602.jpg)
research Effects of Finasteride on Chronic and Acute Ethanol Withdrawal Severity in the WSP and WSR Selected Lines
Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.
![Post-Finasteride Syndrome: Risks and Side Effects of Finasteride for Androgenetic Alopecia](/images/research/8edc3389-299c-48b8-b8b8-9d23d7211b6c/small/4814.jpg)
research Post-Finasteride Syndrome: Risks and Side Effects of Finasteride for Androgenetic Alopecia
Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
![Interventional Studies for Polycystic Ovarian Syndrome in Children and Adolescents](/images/research/9409b7f9-189b-489c-bfa3-3cda7f154764/small/14922.jpg)
research Interventional Studies for Polycystic Ovarian Syndrome in Children and Adolescents
Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.
![Testosterone Therapy in Premenopausal Women](/images/research/227267f9-c9a3-44bc-b2b0-3e98420598cf/small/15237.jpg)
research Testosterone Therapy in Premenopausal Women
Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.
![Altered Methylation Pattern of the SRD5A2 Gene in the Cerebrospinal Fluid of Post-Finasteride Patients: A Pilot Study](/images/research/fa4f583a-7c07-4107-8ce3-d0a424b6b6f4/small/4586.jpg)
research Altered Methylation Pattern of the SRD5A2 Gene in the Cerebrospinal Fluid of Post-Finasteride Patients: A Pilot Study
Finasteride affects SRD5A2 gene pattern, possibly causing lasting side effects.
![Safety and Efficacy of Transdermal Testosterone for Treatment of Hypoactive Sexual Desire Disorder](/images/research/48139902-da69-41a1-bcbb-fd1a518b69ca/small/14629.jpg)
research Safety and Efficacy of Transdermal Testosterone for Treatment of Hypoactive Sexual Desire Disorder
Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.