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Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The Rotterdam Study aims to understand various diseases in older adults.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Androgens can help prevent memory problems caused by apoE4.

Oestrogens are key for bone growth during puberty in both boys and girls.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

CDP is crucial for lung and hair follicle cell development.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.