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Skin diseases are common and can significantly affect people's lives; better outcome measures and ethical clinical trials are needed to improve dermatology care.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.

Thuja orientalis hot water extract may help hair grow by starting the growth phase and improving hair follicle development.

Trastuzumab deruxtecan is effective for HER2-positive breast cancer but requires careful management of side effects.

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

Proactive monitoring and management are essential to maximize the benefits of Trastuzumab Deruxtecan while minimizing serious side effects.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Creating fully functional artificial skin for chronic wounds is still very challenging.

Oral baricitinib and ruxolitinib are effective and safe for treating alopecia areata.

2007 research improved understanding of prostate cancer risk, diagnosis, and treatment, but also showed the need for personalized treatment and further study on certain therapies' risks.

Cetuximab can cause eyelash growth, which is rare but manageable.

Most American men experience hair loss by age 50, with limited effective treatments available and new options not expected soon.

miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.

308 nm excimer light therapy may help hair regrowth in alopecia areata with delayed results and no serious side effects.

Low vitamin D levels might cause hair loss that can be treated with vitamin D supplements.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

The document concludes that various treatments for skin conditions are effective, but some require further research, and certain factors like gender and lifestyle can influence disease outcomes.

Treating psoriasis with UVB light three times a week is faster than twice a week, and certain medications and lifestyle factors affect psoriasis treatment outcomes.

New treatments for lupus show promise, but more research is needed, especially for children.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Vitamin D deficiency is linked to a higher chance of metabolic syndrome in women with PCOS.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

New treatments for relapsing multiple sclerosis are more effective and convenient but have higher risks of serious side effects.

Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

People with alopecia areata have higher levels of RBP4 protein and antibodies against it.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

New therapies are being developed that target integrin pathways to treat various diseases.

Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.