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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

PGD2 stops hair growth and is higher in bald men with AGA.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Finasteride effectively blocks enzyme causing male pattern baldness.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

Finasteride effectively treats baldness but may cause sexual side effects.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.

Flutamide may slightly improve hair loss in women, but finasteride does not work.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

Minoxidil with propranolol and diuretics lowers blood pressure but causes fluid retention and hair growth.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.