research Pharmacokinetic-Pharmacodynamic Modeling Approach for Dose Prediction of the Optimal Long-Acting Injectable Formulation of Finasteride
Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.
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research Male Pattern Baldness: Causes, Treatments, and Future Prospects
Most American men experience hair loss by age 50, with limited effective treatments available and new options not expected soon.
research Index
The document is a detailed medical reference on skin and genetic disorders.
research Nanostructured Drug Delivery Systems for Targeting 5-Alpha-Reductase Inhibitors to the Hair Follicle
Nanostructured delivery systems could potentially improve hair loss treatment by targeting drugs to hair follicles, reducing side effects and dosage, but the best size, charge, and materials for these systems need further investigation.
research Operative Transvaginal Hydrolaparoscopy Improves Ovulation Rate After Clomiphene Failure in Polycystic Ovary Syndrome
Transvaginal hydrolaparoscopy is effective for increasing ovulation and pregnancy rates in women with PCOS who didn't respond to clomiphene.
research Efficacy and Safety of Laser Therapy and Phototherapy in Cicatricial and Non-Cicatricial Alopecia: A Systematic Review Study
Light/laser therapy can effectively increase hair density in some types of alopecia, especially androgenic alopecia and alopecia areata.
research Minoxidil Use in Dermatology, Side Effects, and Recent Patents
Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.
research Update on the Treatment of Alopecia Areata
Some treatments can help hair regrowth in alopecia areata, but none offer a cure, and effectiveness varies.
research Efficacy and Safety of Platelet-Rich Plasma for Acute Nonarteritic Anterior Ischemic Optic Neuropathy: A Prospective Cohort Study
PRP treatment can safely improve short-term vision in acute NAION patients.
research Chronic Treatment with Finasteride Daily Does Not Affect Spermatogenesis or Semen Production in Young Men
Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.
research Common Dermatologic Conditions
The document concludes that quick referral and appropriate treatments are crucial for managing common skin conditions and preventing permanent damage.
research Androgen Excess: A Hallmark of Polycystic Ovary Syndrome
Excess androgens may cause PCOS, not just be a symptom.
research Therapeutic Options in Polycystic Ovary Syndrome
The document suggests various treatments for PCOS, including medication for menstrual issues, insulin resistance, and excess hair, as well as fertility treatments, while highlighting the need for personalized care and lifestyle changes.
research The Efficacy of Using Platelet-Rich Plasma in the Treatment of Androgenic Alopecia: A Literature Review
PRP therapy helps improve hair growth and is safe for treating hair loss.
research Androgenetic Alopecia: In Vivo Models
Stump-tailed macaque best for researching hair loss causes and treatments.
research Author’s Reply to the Comment on: The Effect of Intradermal Botulinum Toxin on Androgenetic Alopecia and Its Possible Mechanism
Botulinum toxin affects hair follicles, inhibiting TGF-B1 secretion; more research ongoing.
research A Novel Hair Restoration Technology Counteracts Androgenic Hair Loss and Promotes Hair Growth in a Blinded Clinical Trial
A new hair restoration technology was found to effectively increase hair thickness, density, and growth, while reducing hair loss and improving scalp health, with no side effects.
research A Phase III, Multicenter, Parallel-Design Clinical Trial to Compare the Efficacy and Safety of 5% Minoxidil Foam Versus Vehicle in Women With Female Pattern Hair Loss
5% minoxidil foam is effective and safe for hair regrowth in women with hair loss.
research Phase III Randomized Clinical Trial Comparing Primary Surgery Versus Neoadjuvant Chemotherapy in Advanced Epithelial Ovarian Cancer With High Tumor Load (SCORPION Trial): Final Analysis of Peri-Operative Outcome
Neoadjuvant chemotherapy followed by surgery leads to fewer severe complications and better quality of life than immediate surgery in advanced ovarian cancer patients with high tumor load.
research Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
research Data from Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The treatment was ineffective in humans.
research Enhancing the Growth of Natural Eyelashes: The Mechanism of Bimatoprost-Induced Eyelash Growth
Bimatoprost is a safe and effective treatment for making eyelashes longer, thicker, and darker.
research Safety and Biopsy Outcomes of a Topical Treatment (SM04554) for Male Androgenetic Alopecia: Results from a Phase 2, Multicenter, Randomized, Double-Blind, Vehicle-Controlled Trial
Topical treatment SM04554 safely promotes hair growth in male baldness.
research Janus Kinase Inhibitors for Alopecia Areata
JAK inhibitors offer new hope for treating severe alopecia areata.
research 5% Minoxidil: Treatment for Female Pattern Hair Loss
5% minoxidil foam effectively treats female hair loss.
research Phase I/IIa Clinical Trial for the Treatment of Androgenetic Alopecia Using Intradermal Injections of Cultured Autologous Dermal Sheath Cup Cells
Injections of special skin cells showed potential in treating hair loss, with some participants experiencing increased hair density.
research Efficacy and Safety of Topical Finasteride Spray Solution for Male Androgenetic Alopecia: A Phase III, Randomized, Controlled Clinical Trial
Topical finasteride is an effective and safer treatment for male hair loss.
research Clinical Snippets: Dermatological Findings and Insights
A hormone affects hair growth, certain molecules may prevent skin damage, a skin disease is linked to immune cells, glycerol helps skin hydration, and psoriasis treatment trials need improvement.
research Quality of Life of Patients with Metastatic Breast Cancer Treated with Epirubicin and Docetaxel
Patients with metastatic breast cancer treated with epirubicin and docetaxel had a good response and maintained their quality of life.
research The Effects of Oral Supplementation with a Natural Keratin Hydrolysate (Kera-Diet) on Hair and Nails: Randomized, Placebo and Benchmark-Controlled Clinical Trial on Healthy Females
Taking Kera-Diet® improves hair and nail health without side effects.